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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TP1045L | Orexin B, rat, mouse Acetate | Rat orexin B,Orexin B (mouse) Acetate,Orexin B, rat, mouse Acetate(202801-92-1 free base) | OX Receptor |
Orexin B, rat, mouse Acetate (Rat orexin B) is an endogenous agonist at Orexin receptor with Kis of 420 and 36 nM for OX1 and OX2, respectively. | |||
T3177 | Orexin 2 Receptor Agonist | OX2R | OX Receptor |
Orexin 2 Receptor Agonist (OX2R) is an effective (EC50: 23 nM) and OX2R-selective (OX1R/OX2R EC50 ratio: 70) agonist. | |||
TP1045 | Orexin B, rat, mouse | Orexin B (mouse),Rat orexin B | |
Orexin B, rat, mouse is an endogenous agonist at Orexin receptor with Kis of 420 and 36 nM for OX1 and OX2, respectively. | |||
TP1139 | Orexin B, human | Human orexin B | |
Orexin B, human is an endogenous agonist at Orexin receptor with Kis of 420 and 36 nM for OX1 and OX2, respectively. Orexin B is a hypothalamatic neuropeptide stimulating food intake in rats. | |||
TP1975 | [Ala11,D-Leu15]-Orexin B(human) | [Ala11,D-Leu15]-Orexin B | |
Highly potent and selective OX2 receptor agonist; displays 400-fold selectivity over OX1 receptors. EC50 values are 0.13 and 52 nM for human OX2 and OX1 receptors respectively. | |||
TP1138 | Orexin B, human TFA (205640-91-1 free base) | Orexin B, human TFA,Human orexin B TFA | |
Orexin B, human (TFA) is an endogenous agonist at Orexin receptor with Kis of 420 and 36 nM for OX1 and OX2. | |||
TP1975L | [Ala11,D-Leu15]-Orexin B acetate | [Ala11,D-Leu15]-Orexin B acetate (532932-99-3 Free base) | OX Receptor |
[Ala11,D-Leu15]-Orexin B acetate is a selective agonist of orexin-2 receptor (OX2) with an EC50 of 0.13 nM, showing 400-fold selectivity over OX1 (52 nM). | |||
T38139 | Orexin receptor antagonist 2 | ||
Orexin Receptor Antagonist 2 (compound 30), characterized by its potent antagonistic activity with pKis of 7.69 and 9.78, holds promise for insomnia research[1]. | |||
T39561 | Orexin 2 Receptor Agonist 2 | ||
Orexin 2 Receptor Agonist 2 (ORA-2) is a specific agonist for the orexin 2 receptor. | |||
TP1301 | Orexin A (human, rat, mouse) | ||
Orexin A human, rat, mouse, a 33 amino acid excitatory neuropeptide, orchestrates diverse central and peripheral processes. Orexin A human, rat, mouse has been used to study its effect on the functioning of porcine pancr... | |||
TP1550 | Orexin A (human, rat, mouse) (TFA) | ||
Endogenous agonist at orexin receptors (Ki values are 20 and 38 nM for OX1 and OX2 receptors respectively). Stimulates feeding following central administration and may be involved in the control of sleep-wake cycle and o... | |||
T62050 | Orexin receptor antagonist 4 | ||
Orexin receptor antagonist 4 is potent and selective orexin 2 receptor (OX2R) antagonist. Orexin receptor antagonist 4 shows IC50 of 4.27 nM and 295 nM for OX2R and OX1R, respectively. | |||
T62453 | Orexin receptor antagonist 3 | ||
Orexin receptor antagonist 3 (example 216) is an orexin receptor antagonist. | |||
T75925 | Orexin B, rat, mouse TFA | ||
Orexin B, rat, mouse (Rat orexin B) TFA, an endogenous agonist for orexin receptors, binds to and activates the closely related orphan G protein-coupled receptors OX1-R and OX2-R. This compound is instrumental in stimula... | |||
T75920 | Orexin B, human TFA | ||
Orexin B, human (TFA), functions as a native agonist for the Orexin receptor, exhibiting dissociation constants (Kis) of 420 nM for OX1 and 36 nM for OX2, respectively. | |||
T79056 | Orexin receptor modulator-1 | ||
Orexin Receptor Modulator-1 is a compound utilized in the study of various conditions including substance addiction, panic disorder, anxiety, post-traumatic stress disorder (PTSD), pain, depression, seasonal affective di... | |||
T73658 | Orexin A (human, rat, mouse) (acetate) | ||
Orexin A (Hypocretin-1) (human, rat, mouse) acetate, a hypothalamic neuropeptide with analgesic abilities that penetrates the blood-brain barrier, acts as an OX1R agonist. It promotes the expression of BDNF and TH protei... | |||
T11186 | EMPA | OX Receptor | |
EMPA is a selective, high-affinity and reversible antagonist of orexin OX2 receptor(human and rat OX2-HEK293 membranes with KD values of 1.1 and 1.4 nM respectively) | |||
T75921 | [Ala11,D-Leu15]-Orexin B(human) TFA | ||
[Ala11,D-Leu15]-Orexin B(human) TFA is a potent, selective agonist for the orexin-2 receptor (OX2), demonstrating 400-fold higher selectivity for OX2 (EC 50 =0.13 nM) compared to the orexin-1 receptor (OX1) with an EC 50... | |||
T5503 | IPSU | OX Receptor | |
IPSU is an antagonist of OX2 receptor. IPSU Exhibits approximately six-fold selectivity for OX2 versus OX1 receptors. |