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Search Results for " nucleolar "

8

Compounds

Cat No. Product Name Synonyms Targets
T35648 4-Thiouridine Others
4-Thiouridine (4-SU) is a photoactivatable ribonucleoside analog that is widely used for RNA analysis, including short-range RNA-RNA crosslinking and nascent RNA labeling. The crosslinking thio moiety is attached directl...
T12006 Metarrestin ML246 DNA/RNA Synthesis
Metarrestin (ML246) is a first-in-class perinucleolar compartment inhibitor with a favorable PK profile, which effectively suppresses metastasis. Metarrestin disrupts the nucleolar structure and inhibits RNA polymerase (...
T23803 BMH-23 BMH23,BMH 23
BMH-23 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.
T23802 BMH-22 BMH22
BMH-22 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.
T68859 Rudolfomycin
Rudolfomycin is a class II anthracycline antitumor antibiotic that inhibit the synthesis of nucleolar RNA in intact tumor cells.
T23804 BMH-9 BMH 9
BMH-9 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.
T73724 WDR5-IN-4 TFA
WDR5-IN-4 TFA is an inhibitor of the WIN site of chromatin-associated WD repeat-containing protein 5 ( WDR5 ), with a K d of 0.1 nM. WDR5-IN-4 TFA displaces WDR5 from chromatin and decreases the expression of associated ...
T69908 Pidnarulex HCl
Pidnarulex HCl is the salt form of CX-5461, a first-in-class non-genotoxic small molecule targeted inhibitor of RNA polymerase I (Pol I) that activates the p53 pathway without causing DNA damage. CX-5461 selectively inhi...
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