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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T79321 | nSMase2-IN-1 | Phospholipase | |
nSMase2-IN-1 is an orally active inhibitor of Neutral sphingomyelinase 2 (nSMase2) with a potent IC50 value of 0.13 ± 0.06 μM. It demonstrates metabolic stability in liver microsomes and possesses a favorable brain-to-pl... | |||
T4985 | Neticonazole Hydrochloride | Antifungal | |
Neticonazole Hydrochloride is an imidazole antifungal for the treatment of fungal skin infections. Neticonazole is reported as a potent exosome inhibitor which can block the activity of exosomes. | |||
T69756 | GT-2331 | ||
GT-2331 is a histamine H3 receptor antagonist. | |||
T69757 | PDDC inhibitor | ||
PDDC is the first nSMase2 inhibitor that possesses both favorable pharmacodynamics and pharmacokinetic (PK) parameters, including substantial oral bioavailability, brain penetration, and significant inhibition of exosome... |