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Search Results for " nsmase2 "

4

Compounds

Cat No. Product Name Synonyms Targets
T79321 nSMase2-IN-1 Phospholipase
nSMase2-IN-1 is an orally active inhibitor of Neutral sphingomyelinase 2 (nSMase2) with a potent IC50 value of 0.13 ± 0.06 μM. It demonstrates metabolic stability in liver microsomes and possesses a favorable brain-to-pl...
T4985 Neticonazole Hydrochloride Antifungal
Neticonazole Hydrochloride is an imidazole antifungal for the treatment of fungal skin infections. Neticonazole is reported as a potent exosome inhibitor which can block the activity of exosomes.
T69756 GT-2331
GT-2331 is a histamine H3 receptor antagonist.
T69757 PDDC inhibitor
PDDC is the first nSMase2 inhibitor that possesses both favorable pharmacodynamics and pharmacokinetic (PK) parameters, including substantial oral bioavailability, brain penetration, and significant inhibition of exosome...
TargetMol