endonuclease — TargetMol Chemicals

Cat No.	Product Name	Targets
T63808	Cap-dependent endonuclease-IN-1	Others
	Cap-dependent endonuclease-IN-1 is a highly potent and orally active cap-dependent endonuclease inhibitor with antiviral activity for the study of influenza virus infection.	Others
T60379	PUL89 Endonuclease-IN-1
	pUL89 Endonuclease-IN-1 (Compound 13d), with an IC50 value of 0.88 μM, serves as a potent inhibitor of human cytomegalovirus (HCMV) pUL89 endonuclease, demonstrating antiviral activity [1].
T61840	PUL89 Endonuclease-IN-2
	pUL89 Endonuclease-IN-2 (Compound 15k) is a highly effective inhibitor of the pUL89 endonuclease of human cytomegalovirus (HCMV). With an IC50 of 3.0 μM, it exhibits potent antiviral activities [1].
T61757	Cap-dependent endonuclease-IN-26
	Cap-dependent endonuclease-IN-26, a potent inhibitor of cap-dependent endonuclease (CEN) with an IC50 of 286 nM, exhibits significant antiviral activity against a broad spectrum of influenza A and B strains [1].
T72117	Cap-dependent endonuclease-IN-15
	Cap-dependent endonuclease-IN-15 is a potent inhibitor of cap-dependent endonuclease (CEN), effectively hindering the replication of influenza virus. This compound shows promise for the investigation of viral infections...
T64177	Cap-dependent endonuclease-IN-2
	Cap-dependent endonuclease-IN-2 is a potent inhibitor of cap-dependent nucleic acid endonucleases (CEN). Cap-dependent endonuclease-IN-2 significantly inhibits influenza A virus RNA polymerase activity.
T72124	Cap-dependent endonuclease-IN-7
	Cap-dependent endonuclease-IN-7 is a potent inhibitor of cap-dependent endonuclease (CEN), effectively inhibiting viral mRNA synthesis and subsequently halting virus proliferation. This compound is specifically promising...
T64213	Cap-dependent endonuclease-IN-3
	Cap-dependent endonuclease-IN-3 is a potent inhibitor of cap-dependent nucleic acid endonucleases (CEN). Cap-dependent endonuclease-IN-3 has shown potential for the investigation of influenza A and B infections.
T62150	Cap-dependent endonuclease-IN-25
	Cap-dependent endonuclease-IN-25 is a macrocyclic pyridoxal derivative and a potent inhibitor of cap-dependent nucleic acid endonucleases (CEN). The Cap-dependent endonuclease IN-25 has potential for the study of viral i...
T74295	Cap-dependent endonuclease-IN-22
	Cap-dependent endonuclease-IN-22 is a powerful inhibitor of cap-dependent endonuclease (CEN) [1].
T62208	Cap-dependent endonuclease-IN-6
	Cap-dependent endonuclease-IN-6 (compound 13) is a Cap-dependent endonuclease (CEN) inhibitor that inhibits influenza virus.
T64138	Cap-dependent endonuclease-IN-16
	Cap-dependent endonuclease-IN-16 is a pyridone polycyclic derivative and a potent inhibitor of cap-dependent nucleic acid endonucleases (CEN). cap-dependent endonuclease-IN-16 shows potential for influenza studies.
T74294	Cap-dependent endonuclease-IN-12
	Cap-dependent Endonuclease-IN-12 (EXP-35) is a potent inhibitor of Cap-dependent endonuclease, demonstrating low cytotoxicity. This compound exhibits inhibitory effects on H1N1 [1].
T63703	Cap-dependent endonuclease-IN-23
	Cap-dependent endonuclease-IN-23 is a potent inhibitor of cap-dependent nucleic acid endonucleases (CEN) and has inhibitory effects on influenza virus replication. cap-dependent endonuclease-IN-21 shows research potentia...
T63673	Cap-dependent endonuclease-IN-10
	Cap-dependent endonuclease-IN-10 is a potent inhibitor of cap-dependent nucleic acid endonucleases (CEN). cap-dependent endonuclease-IN-10 effectively inhibits influenza viruses with low cytotoxicity, good in vivo pharma...
T63910	Cap-dependent endonuclease-IN-5
	Cap-dependent endonuclease-IN-5 is a potent inhibitor of cap-dependent nucleic acid endonucleases (CEN). cap-dependent endonuclease-IN-5 has good influenza virus inhibitory activity and/or has lower cytotoxicity, better ...
T63981	Cap-dependent endonuclease-IN-17
	Cap-dependent endonuclease-IN-17 is a cap-dependent endonuclease (CEN) inhibitor. cap-dependent endonuclease-IN-17 exhibits antiviral activity (IC50: 1.29 μM) against influenza virus A/Hanfang/359/95 (H3N2).
T63073	Cap-dependent endonuclease-IN-19
	Cap-dependent endonuclease-IN-19 is a spirocyclic pyridinone derivative and a potent inhibitor of cap-dependent nucleic acid endonuclease (CEN). cap-dependent endonuclease-IN-19 potently inhibits the RNA polymerase activ...
T63680	Cap-dependent endonuclease-IN-11
	Cap-dependent endonuclease-IN-11 is a potent inhibitor of cap-dependent nucleic acid endonucleases (CEN). cap-dependent endonuclease-IN-11 has shown research potential for viral infections.
T63519	Cap-dependent endonuclease-IN-13
	Cap-dependent endonuclease-IN-13 is a potent inhibitor of cap-dependent endonuclease (CEN) and shows research potential against influenza virus infection (influenza A only).