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Search Results for " eif-4e "

Targets

5

Compounds

1

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T1742 4E1rcat PERK , Autophagy
4E1RCat is a dual inhibitor of eIF4E:eIF4 g and eIF4E:4E-BP1 interaction. And it inhibits the binding of eIF4 g to eIF4E with IC50 of 3.2 μM.
T14044 4E2RCat PERK
4E2RCat is an eIF4E-eIF4G interaction inhibitor (IC50: 13.5 μM).
T40211 eIF4E-IN-1 eIF4E-IN-1
eIF4E-IN-1 (WO2021003194A1, compound Y), is a highly effective inhibitor of eIF4E, a key protein involved in immunosuppression. By targeting immune checkpoint proteins such as PD-1, PD-L1, LAG3, TIM3, and IDO, eIF4E-IN-1...
T40210 eIF4E-IN-3 eIF4E-IN-3
eIF4E-IN-3 is a highly effective inhibitor of eukaryotic initiation factor 4e (eIF4e), exhibiting noteworthy potential for investigating eIF4e dependent diseases, particularly cancer research (WO2021003157A1, compound 48...
T40214 eIF4E-IN-2 eIF4E-IN-2
eIF4E-IN-2 is a highly effective inhibitor of eukaryotic initiation factor 4e (eIF4e). This compound exhibits significant potential in the investigation of eIF4e dependent diseases, particularly in the context of cancer ...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPJ-00507 EIF4E Protein, Human, Recombinant Human E. coli
Eukaryotic translation initiation factor 4E is a 217 amino acids protein that belongs to the eukaryotic initiation factor 4E family. eIF4F is a multi-subunit complex, the composition of which varies with external and int...
TargetMol