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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2345 | PTC-209 | PTC209,PTC 209 | BMI-1 , Autophagy |
PTC-209 is a potent and selective BMI-1 inhibitor. | |||
T6178 | PTC-209 hydrobromide | PTC-209 HBr | BMI-1 , Autophagy |
PTC-209 hydrobromide (PTC-209 HBr) is the hydrobromide salt of PTC-209, which is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM, and results in irreversible reduction of cancer-initiating cells (CICs). | |||
T38637 | Roy-Bz | ||
Roy-Bz is a potent and selective activator of protein kinase C delta (PKCδ). It effectively inhibits proliferation in colon cancer cells by initiating a mitochondrial apoptotic pathway that relies on PKCδ and involves th... | |||
T36485 | Becatecarin | ||
Becatecarin is a water-soluble, diethylaminoethyl analog of the antineoplastic antibiotic rebeccamycin. It intercalates into DNA, stabilizing the DNA-topoisomerase complex. This results in the potent catalytic inhibition... | |||
T35940 | Darinaparsin | Dimethylarsinic glutathione,Darinaparsin | |
Darinaparsin is a dimethylated arsenic linked to glutathione. It is cytotoxic to DU145, LNCaP, and PC3 prostate cancer cells (IC50s = 5-10 µM) and patient-derived primary prostate cancer cells (IC50s = 2.5-20 µM)... | |||
T79558 | Fac-[Re(CO)3(L3)(H2O)][NO3] | ||
Fac-[Re(CO)3(L3)(H2O)][NO3] (Compound 3), a rhenium(I) tricarbonyl aqua complex, acts as an anticancer agent through the induction of mitochondrial dysfunction. It exhibits cytotoxicity against prostate cancer cells, dem... |