amyloidogenic — TargetMol Chemicals

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Search Results for " amyloidogenic "

Compounds

Cat No.	Product Name	Synonyms	Targets
T22118	NQTrp		Microtubule Associated
	NQTrp is an inhibitor of the aggregation of the tau protein with generic anti-amyloidogenic effects.		Microtubule Associated
T4565	Tafamidis	Fx-1006A	Others
	Tafamidis (Fx-1006A) is a kinetic stabilizer of transthyretin (TTR) that prevents amyloidogenesis by wild-type and mutant TTRs. It binds to TTR with negative cooperativity (Kd1: 3 nM; Kd2: 278 nM) to stabilize the TTR di...		Others
T28110	MRZ-99030	EG 030,EG030,EG-030,MRZ 99030
	MRZ-99030 is an Aβ aggregation modulator. MRZ-99030 triggers a non-amyloidogenic aggregation pathway, thereby reducing the amount of intermediate toxic soluble oligomeric Aβ species.
T28336	PD 142505-0028	CI 1017,CI1017,CI-1017,PD-142505-0028,PD42505-0028
	PD 142505-0028, a functionally M1-selective muscarinic agonist, rapidly increases glutamate but not aspartate concentrations in the striatum of anesthetized rats. Additionally, it inhibited production of amyloidogenic A ...
T72285	LC kinetic stabilizer-1
	LC kinetic stabilizer-1 is a potent, selective kinetic stabilizer for amyloidogenic immunoglobulin light chains, demonstrating EC50 values of 140 nM for WIL-FL* and 74.1 nM for WIL-FL*T46L/F49Y, respectively. Notably, WI...
T76659	Acetyl-PHF5 amide
	Acetyl-PHF5 amide is a tau peptide with amyloidogenic properties. It can undergo polymerization to form filamentous structures [1].
T72286	LC kinetic stabilizer-2
	LC Kinetic Stabilizer-2 is a powerful stabilizer for amyloidogenic immunoglobulin light chains (LC), demonstrating significant efficacy with an EC50 of 24 nM.
T81138	SNNF(N-Me)GA(N-Me)ILSS
	SNNF(N-Me)GA(N-Me)ILSS is a biologically active peptide comprising double N-methylated derivatives of an amyloidogenic and cytotoxic partial IAPP sequence.
T39638	Eprodisate
	Eprodisate is a novel compound specifically developed to disrupt the interactions between amyloidogenic proteins and glycosaminoglycans, effectively impeding the polymerization of amyloid fibrils and their deposition in ...
TP1228	β-Amyloid (1-16)	Amyloid β-Protein (1-16),β-Amyloid 1-16
	β-Amyloid (1-16) is an amyloidogenic protein fragment with a sequence derived from β-amyloid. It exhibits the ability to bind to metal ions, indicating its involvement in metal-binding processes. β-Amyloid, a peptide, is...
T81139	SNNF(N-Me)GA(N-Me)IL
	SNNF(N-Me)GA(N-Me)IL is a biologically active peptide comprising double N-methylated derivatives of a partial IAPP sequence known to be amyloidogenic and cytotoxic.
T81678	NF(N-Me)GA(N-Me)IL	Amylin (22-27) [NMeG24, NMeI26], human (IAPP)
	NF(N-Me)GA(N-Me)IL is a biologically active peptide, representing a modified segment (amino acids 22 to 27) of the human islet amyloid polypeptide (hIAPP) sequence NFGAIL. This modification includes N-methylations at G24...
T36911	Pramlintide (acetate hydrate)
	Pramlintide is a non-amyloidogenic analog of the antidiabetic peptide hormone amylin that contains proline residues substituted at positions 25, 28, and 29. It stimulates cAMP production in HEK293 cells expressing human ...