4
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T17249 | VZ185 | Epigenetic Reader Domain | |
VZ185 is an effective and selective dual BRD7/9 PROTAC degrader (DC50s: 4.5 and 1.8 nM, respectively). | |||
T41201 | Cis-VZ 185 | ||
cis-VZ 185 is a negative control for VZ 185. | |||
T17697 | BRD7-IN-1 | Epigenetic Reader Domain | |
BRD7-IN-1, a modified derivative of BI7273 (BRD7/9 inhibitor), forms PROTAC VZ185 through linkage to a VHL ligand, demonstrating potent activity against BRD7/9 with DC50 values of 4.5 and 1.8 nM, respectively [1]. | |||
T17696 | BRD7-IN-1 free base | Others | |
BRD7-IN-1 free base, a modified derivative of BI7273 (BRD7/9 inhibitor), interacts with a VHL ligand through a linker, constituting the PROTAC VZ185 (targeting BRD7/9 with DC50 values of 4.5 and 1.8 nM, respectively)[1]. |