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Search Results for " trk-in-10 "

4

Compounds

Cat No. Product Name Synonyms Targets
T61872 Trk-IN-10
Trk-IN-10 (Compound 14j) is a highly effective inhibitor of TRK, with an IC50 of 0.86 nM against TrkA and 6.92 nM against TrkA G595R. As an RTK, Trk plays a crucial role as a drug target in solid tumors. Trk-IN-10 (IC50 ...
T19649 PF-06273340 PF 6273340,PF 06273340,PF6273340,PF-6273340 Trk receptor
PF-06273340 is an effective, Selective, and Peripherally Restricted Pan-Trk inhibitor (IC50: Trk-A = 6 nM; Trk-B = 4 nM; Trk-C = 3 nM). PF-06273340 has low metabolic turnover in HLM and hHep is a good substrate for efflu...
T62095 TRK-IN-19
TRK-IN-19 (Compound I-10 ) is a potent inhibitor of TRK with IC50 values of 1.1 nM for TRKA and 5.3 nM for TRKAG595R. TRK-IN-19 has shown potential research value in cancer disease.
T61443 Trk-IN-7
Trk-IN-7 (compound I-6) is a highly potent inhibitor of TRK, exhibiting IC50 values ranging from 0.25-10 nM for TRKA, TRKB, and TRKC, respectively. In addition, Trk-IN-7 demonstrates notable inhibition against EML4-ALK (...
TargetMol