tph — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T39578	TPh A	Triphenyl Compound A
	Triphenyl Compound A (TPh A) is an effective inhibitor of nuclear protein pirin, showing specific binding to pirin with a Ki value of 0.6 uM. Its mechanism of action involves disturbing the formation of the bcl3–pirin co...
T10142L	P-Ethynylphenylalanine hydrochloride	4-Ethynyl-L-phenylalanine HCL,p-Ethynylphenylalanine hydrochloride(278605-15-5 free base)	Hydroxylase
	p-Ethynylphenylalanine hydrochloride (4-Ethynyl-L-phenylalanine HCL) is a novel, potent and specific inhibitor of TPH[1]. The potential for p-Ethynylphenylalanine hydrochloride to inhibit selectively and reversibly the b...		Hydroxylase
T19936	Xantphos
	Xantphos, a ligand in the coupling reaction of Buchwald, Suzuki and others, is a metal chelating ligand that can be used to catalyze the reaction.
T64621	(tBuBrettPhos Pd(allyl))TfOH salt
	(tBuBrettPhos Pd(allyl))TfOH salt is a useful organic compound for research related to life sciences and the catalog number is T64621.
T67255	AdBrettPhos Pd G3
	AdBrettPhos Pd G3 is a useful organic compound for research related to life sciences and the catalog number is T67255.
T67254	N-XantPhos Pd G3
	Methanesulfonato[4,6-bis(diphenylphosphino)phenoxazine](2'-amino-1,1'-biphenyl-2-yl)palladium(II) is a useful organic compound for research related to life sciences and the catalog number is T67254.
T67260	XantPhos Pd G4
	Methanesulfonato[9,9-dimethyl-4,5-bis(diphenylphosphino)xanthene](2'-methylamino-1,1'-biphenyl-2-yl)palladium(II) is a useful organic compound for research related to life sciences and the catalog number is T67260.
T64764	BrettPhos Pd G4
	BrettPhos Pd G4 is a useful organic compound for research related to life sciences. The catalog number is T64764 and the CAS number is 1599466-83-7.
T64584	TBuBrettPhos Pd G3
	[(2-Di-tert-butylphosphino-3,6-dimethoxy-2',4',6'-triisopropyl-1,1'-biphenyl)-2-(2'-amino-1,1'-biphenyl)]palladium(II) methanesulfonate is a useful organic compound for research related to life sciences. The catalog numb...
T79712	TPH1-IN-1
	TPH1-IN-1 (compound 40) is a xanthine derivative that serves as an inhibitor of tryptophan hydroxylase TPH1, with an IC50 of 110.1 nM. Demonstrating robust in vitro activity and liver microsome stability, it effectively ...
T14119	ACT-678689	Compound Example 1.53.4	Hydroxylase
	ACT-678689 (Compound Example 1.53.4) (Compound Example 1.53.4) is a tryptophan hydroxylase (TPH) inhibitor with an IC50 of 8 nM[1].		Hydroxylase
T21506	Telotristat		Hydroxylase
	Telotristat is the active metabolite of LX1606(Telotristat etiprate), which is an orally bioavailable tryptophan hydroxylase (TPH) inhibitor and shows potential antiserotonergic activity.		Hydroxylase
T10142	P-Ethynylphenylalanine	4-Ethynyl-L-phenylalanine	Others , Hydroxylase
	p-Ethynylphenylalanine (4-Ethynyl-L-phenylalanine), a tryptophan hydroxylase (TPH) inhibitor, is competitive, effective, selective, and reversible, with a Ki of 32.6 μM.		Others , Hydroxylase
T6044	Telotristat Etiprate	LX1606 (Hippurate),LX 1606 Hippurate	Hydroxylase
	Telotristat Etiprate (LX 1606 Hippurate) is an orally bioavailable, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity.		Hydroxylase
T6004	Tetrahydropapaverine hydrochloride	Tetrahydropapaverine HCl,Norlaudanosine HCl,Tetrahydroalkali hydrochloride	Hydroxylase
	Tetrahydropapaverine hydrochloride (Norlaudanosine HCl) , an analogue of salsolinol and tetrahydropapaveroline, has neurotoxicity on dopamine neurons.		Hydroxylase
T69135	AGN-2979
	AGN-2979 is a tryptophan hydroxylase (TPH) activation inhibitor that shows antidepressant properties in rodent models of depression.
T80960	TPT-004
	TPT-004, a TPH inhibitor, exhibits superior pharmacokinetic and pharmacodynamic properties, and demonstrates efficacy in preclinical models for attenuating peripheral serotonin [1] and impeding colorectal tumor growth.