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Cat No. | Product Name | Synonyms | Targets |
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T78688 | HPK1-IN-35 | ||
HPK1-IN-35 is a potent, selective inhibitor of HPK1, demonstrating an IC50 value of 3.5 nM. This compound reduces p-SLP76 expression and facilitates the secretion of IL-2 [1]. | |||
T78852 | HPK1-IN-39 | ||
HPK1-IN-39 (Compound 10n), a selective inhibitor of Hematopoietic Progenitor Kinase 1 (HPK1) with an inhibitory concentration (IC50) of 29 nM, impedes the phosphorylation of SLP76. This compound is applicable in the rese... | |||
T62927 | HPK1-IN-22 | ||
HPK1-IN-22 (compound ZYF0033) is a haematopoietic progenitor kinase 1 (HPK1) inhibitor with an IC50 of less than 10 nM for MBP protein-based phosphorylation inhibition. HPK1-IN-22 reduces phosphorylation of SLP76 (serine... |
Cat No. | Product Name | Species | Expression System |
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TMPJ-01096 | SLP-76 Protein, Human, Recombinant (His) | Human | E. coli |
Lymphocyte cytosolic protein 2(LCP2)contains a SAM domain and a SH2 domain. It is highly expressed in spleen, thymus and peripheral blood leukocytes, T-cell and monocytic cell lines, but expressed at lower level in B-cel... |