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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T28784 | SIRT6-IN-1 | ||
SIRT6-IN-1, a novel SIRT6 inhibitor, reduces glycemia and improves oral glucose tolerance in unfed wild-type mice. | |||
T4328 | OSS_128167 | SIRT6-IN-1 | HBV , Sirtuin |
OSS_128167 (SIRT6-IN-1) is a specific SIRT6 inhibitor, and for SIRT6(IC50=89 μM), SIRT1(IC50=1578 μM) and SIRT2(IC50=751 μM). | |||
T79689 | SIRT6-IN-3 | Sirtuin | |
SIRT6-IN-3 (compound 8a), a selective SIRT6 inhibitor (IC50 = 7.49 μM), impedes the proliferation of pancreatic ductal adenocarcinoma (PDAC) cells and prompts apoptosis. It enhances the responsiveness of cancer cells to ... | |||
T81831 | MDL-811 | Sirtuin | |
MDL-811, an allosteric activator of SIRT6, markedly enhances the deacetylation of histone H3 at lysine residues 9, 18, and 56 (H3K9Ac, H3K18Ac, and H3K56Ac), presenting potential utility in colorectal cancer research [1]... |