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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4687 | Ro5-3335 | CBFβ-Runx1 inhibitor II,Ro 5-3335 | DNA/RNA Synthesis |
Ro5-3335 (CBFβ-Runx1 inhibitor II) is core binding factor (CBF) inhibitor; preferentially kills human leukemia cell lines with CBF fusion proteins (IC50 = 1.1 μM). Ro5-3335 represses RUNX1/CBFβ-dependent transactivation ... | |||
T69677 | Mitapivat sulfate anhydrous | ||
Mitapivat sulfate anhydrous is an allosteric activator of Pyruvate Kinase (PK) that may be useful in the treatment of Pyruvate Kinase Deficiency. | |||
T69678 | WUN40378 | ||
WUN40378 is compound first reported in PCT Int. Appl. (2019), WO 201909959, in which it was described as CBFβ-RUNX1 inhibitor. WUN40378 is very similar to Ro 5-3335 but with an F instead of Cl. WUN40378 is also analog of... |