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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T81269 | RIPK1-IN-16 | RIP kinase | |
RIPK1-IN-16 is an orally active, potent RIPK1 inhibitor that mitigates excessive inflammation via inhibition of RIPK1-mediated necroptosis in vivo. It shields mice from TNF-induced systemic inflammatory response syndrome... | |||
T12730 | RIPK1-IN-4 | RIP kinase | |
RIPK1-IN-4 is a potent and selective type II kinase receptor interacting protein 1 (RIP1) kinase inhibitor and binds to a DLG-out inactive form of RIP1 (IC50s of 16 nM and 10 nM for RIP1 and ADP-Glo kinase). |