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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8767 | PfDHODH-IN-2 | Dehydrogenase , Parasite | |
PfDHODH-IN-2 is a dihydrothiophenone derivative, is a potent Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH, IC50 : 1.11 μM) inhibitor . It is used an antimalarial agent and can be used for the research of m... | |||
T12438 | PfDHODH-IN-1 | Dehydrogenase , Parasite | |
PfDHODH-IN-1 is an analogue of the active Leflunomide metabolite, has antimalarial activity. | |||
T11027 | DHODH-IN-4 | Dehydrogenase | |
DHODH-IN-4 is a human and Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) inhibitor. The IC50 values of PfDHODH and HsDHODH are 4 μM and 0.18 μM, respectively. DHODH-IN-4 has antimalarial activity. | |||
T25524 | IDI-3783 | ||
IDI-3783 is a mutant-selective inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH). | |||
T25448 | Genz-669178 | ||
Genz-669178 is a wild-type inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH). | |||
T24122 | GW648495 | DSM-1,GW-648495,DSM 1,GW 648495,DSM1 | |
GW648495 is a PfDHODH inhibitor that shows greater than 4,000-fold selectivity for the malarial enzyme. | |||
T71061 | DSM267 | ||
DSM267 is a novel Plasmodium falciparum Dihydroorotate Dehydrogenase (PfDHODH) Inhibitor. | |||
T26900 | BRD7539 | BRD-7539,BRD 7539 | |
BRD7539B is a Dihydroorotate dehydrogenase (DHODH) inhibitor . RD7539 shows to target PfDHODH (IC50 = 0.033 μM) selectively over human (Hs) DHODH (IC50 > 50 μM). | |||
T15173 | DSM265 | PfSPZ | Dehydrogenase , Parasite |
DSM265 (PfSPZ) is a dihydroorotic acid dehydrogenase inhibitor with antimalarial activity (IC50: 8.9 nM).DSM265 inhibits the growth of Pf3D7 parasites and can be used for the treatment and prophylaxis of malaria infectio... |