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Search Results for " pfdhodh "

9

Compounds

Cat No. Product Name Synonyms Targets
T8767 PfDHODH-IN-2 Dehydrogenase , Parasite
PfDHODH-IN-2 is a dihydrothiophenone derivative, is a potent Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH, IC50 : 1.11 μM) inhibitor . It is used an antimalarial agent and can be used for the research of m...
T12438 PfDHODH-IN-1 Dehydrogenase , Parasite
PfDHODH-IN-1 is an analogue of the active Leflunomide metabolite, has antimalarial activity.
T11027 DHODH-IN-4 Dehydrogenase
DHODH-IN-4 is a human and Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) inhibitor. The IC50 values of PfDHODH and HsDHODH are 4 μM and 0.18 μM, respectively. DHODH-IN-4 has antimalarial activity.
T25524 IDI-3783
IDI-3783 is a mutant-selective inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH).
T25448 Genz-669178
Genz-669178 is a wild-type inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH).
T24122 GW648495 DSM-1,GW-648495,DSM 1,GW 648495,DSM1
GW648495 is a PfDHODH inhibitor that shows greater than 4,000-fold selectivity for the malarial enzyme.
T71061 DSM267
DSM267 is a novel Plasmodium falciparum Dihydroorotate Dehydrogenase (PfDHODH) Inhibitor.
T26900 BRD7539 BRD-7539,BRD 7539
BRD7539B is a Dihydroorotate dehydrogenase (DHODH) inhibitor . RD7539 shows to target PfDHODH (IC50 = 0.033 μM) selectively over human (Hs) DHODH (IC50 > 50 μM).
T15173 DSM265 PfSPZ Dehydrogenase , Parasite
DSM265 (PfSPZ) is a dihydroorotic acid dehydrogenase inhibitor with antimalarial activity (IC50: 8.9 nM).DSM265 inhibits the growth of Pf3D7 parasites and can be used for the treatment and prophylaxis of malaria infectio...
TargetMol