Home Tools
Log in
Cart

Search Result

Search Results for " pu.1-in-1 "

8

Compounds

Cat No. Product Name Synonyms Targets
T73585 PU.1-IN-1
PU.1-IN-1 is a potent PU.1 inhibitor (IC50 : 2 nM) with anti-inflammatory activity.
T10964 DB1976 Apoptosis , Others
DB1976 is a selenophene analog of DB270 and a potent and cell-permeable fully efficacious transcription factor PU.1 inhibitor. DB1976 potently inhibits PU.1 binding (IC50 of 10 nM) and strongly inhibits the PU.1/DNA comp...
T69842 DB2313 HCl
DB2313 is a first-in-class potent small-molecule inhibitor of PU.1. DB2313 disrupts the interaction of PU.1 with target gene promoters and leads to down-regulation of canonical PU.1 transcriptional targets.
T38778 DB2115 tertahydrochloride DB2115 tertahydrochloride
DB2115 (tertahydrochloride) is a powerful inhibitor of the myeloid master regulator PU.1. With significant potential in cancer research, particularly hematologic cancers like leukemia, as well as other conditions linked ...
T10964L DB1976 dihydrochloride DB1976 hydrochloride,DB1976 2HCl Apoptosis , NF-κB
DB1976 dihydrochloride (DB1976 2HCl) , a transcription factor PU.1 inhibitor with potential anti-inflammatory activity, slowed down inflammation and fibrosis and improved glucose homeostasis and dyslipidemia in mice in i...
T78201 PU-48
PU-48 is a potent inhibitor of urea transporters A (UT-A) with an IC50 value of 0.32 μM, exhibiting a significant diuretic effect in mouse models without notable cytotoxicity. This compound has the potential for further ...
T14293 Annonacin Others
Annonacin is an Acetogenin and promotes cytotoxicity via a pathway inhibiting the mitochondrial complex and it is the active agent found in Graviola leaf extract to act as an inhibitor of sodium/potassium (NKA) and sarco...
T38021 Obafluorin
Obafluorin is a β-lactone antibiotic that has been found in P. fluorescens.1 It is active against S. aureus, S. faecalis, K. pneumoniae, and P. vulgaris (MIC = 125 μg/ml for all). |1. Pu, Y., Lowe, C., Sailer, M., et al....
TargetMol