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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4340 | SPI-112 | Phosphatase | |
SPI-112, the SPI-112 methyl ester analog, can inhibit cellular Shp2 PTP activity. SPI-112 bound to Shp2 by surface plasmon resonance (SPR) and displayed competitive inhibitor kinetics to Shp2. | |||
T13176 | TNO155 | Batoprotafib | Phosphatase |
TNO155 is a protein tyrosine phosphatase (PTP) non-receptor type 11 (SHP2; src homology region 2 domain phosphatase; PTPN11) inhibitor(IC50 : 0.011 µM),with potential antineoplastic activity. | |||
T12903 | SHP2 IN-1 | Others | |
SHP2 IN-1 is an allergic SHP2 (PTPN11) inhibitor(IC50 : 3 nM). | |||
T39167 | GS-493 | ||
GS-493, a highly specific protein tyrosine phosphatase SHP2 (PTPN11) inhibitor, exhibits remarkable potency with an IC50 of 71 nM. It displays 29- and 45-fold greater affinity towards SHP2 compared to its related counter... |