20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T39008 | PRMT5-IN-4 | PRMT5-IN-4 | |
PRMT5-IN-4 (compound AAA-1) is a PRMT5 inhibitor. | |||
T39809 | PRMT5-IN-14 | PRMT5-IN-14 | |
PRMT5-IN-14 is a PRMT5 inhibitor to treat cancer, sickle cell, and hereditary persistence of foetal hemoglobin (HPFH) mutations. | |||
T40197 | PRMT5-IN-11 | PRMT5-IN-11 | |
PRMT5-IN-11 demonstrates potent structure-dependent inhibition against the protein methyltransferase PRMT5:MEP50 complex at submicromolar concentrations. | |||
T40202 | PRMT5-IN-12 | PRMT5-IN-12 | |
PRMT5-IN-12 shows remarkable inhibitory activity on PRMT5 . | |||
T39934 | PRMT5-IN-13 | PRMT5-IN-13 | |
PRMT5-IN-13 is a selective inhibitor of protein arginine methyltransferase 5 (prmt5) . | |||
T39993 | PRMT5-IN-15 | PRMT5-IN-15 | |
PRMT5-IN-15 is a PRMT5 inhibitor with an IC 50 value of 0.84 nM. | |||
T40313 | PRMT5-IN-9 | PRMT5-IN-9 | |
PRMT5-IN-9 is a novel PRMT5 inhibitor for treating cancer, with an IC 50 of 0.01 μM. | |||
T16577 | PRMT5-IN-2 | Histone Methyltransferase | |
PRMT5-IN-2 is an inhibitor of protein arginine methyltransferase 5. | |||
T12541 | PRMT5-IN-1 | Histone Methyltransferase | |
PRMT5-IN-1 is a covalent inhibitor of protein arginine methyltransferase 5 (PRMT5)(IC50 of 11 nM for PRMT5/MEP50). | |||
T69430 | PRMT5-IN-C17 | ||
PRMT5-IN-C17 is a novel potent, selective, and cell active protein arginine methyltransferase 5 (PRMT5) inhibitor. | |||
T62683 | PRMT5-IN-3 | ||
PRMT5-IN-3 is a PRMT5 inhibitor.PRMT5-IN-3 is a combined DNA damaging agent that is synthetically lethal to tumor cells. | |||
T63103 | PRMT5-IN-17 | ||
PRMT5-IN-17 (Compound 6) is a PRMT5 inhibitor that exhibits antitumour activity. PRMT5, a protein arginine methyltransferase, is a novel anti-tumour target associated with epigenetic modifications. | |||
T78152 | PRMT5-IN-25 | Histone Methyltransferase | |
PRMT5-IN-25 (compound 503) is a potent inhibitor of PRMT5, exhibiting an inhibition constant (K i) of 0.06 nM and demonstrating antiproliferative properties [1]. | |||
T63860 | PRMT5-IN-18 | ||
PRMT5-IN-18 (Compound 002) is a potent inhibitor of PRMT5 and can be used in the study of PRMT5-mediated diseases, such as tumours. | |||
T61986 | PRMT5-IN-21 | ||
PRMT5-IN-21 (compound 1) is a potent inhibitor of cyclonucleoside PRMT5. | |||
T60725 | PRMT5-IN-10 | ||
PRMT5-IN-10 exhibits promising structure-dependent inhibitory effect on the protein methyltransferase PRMT5:MEP50 complex. | |||
T76413 | PRMT5-IN-22 | ||
PRMT5-IN-22 (compound 53), an inhibitor of protein arginine methyltransferase 5 (PRMT5), exhibits anti-tumor activity. As a protein arginine methyltransferase, PRMT5 represents a novel anti-tumor target associated with e... | |||
T78172 | PRMT5-IN-29 | Histone Methyltransferase | |
PRMT5-IN-29 is a potent, orally active inhibitor of PRMT5, exhibiting an IC50 value of 1.5 μM, showing promise for use in advanced cancer research [1]. | |||
T79035 | PRMT5-IN-28 | Histone Methyltransferase | |
PRMT5-IN-28 (compound 36) serves as an inhibitor of the protein arginine methyltransferase 5 (PRMT5) enzyme, which is implicated in various cellular processes including gene transcription, mRNA splicing, DNA repair, prot... | |||
T63138 | PRMT5-IN-16 | ||
PRMT5-IN-16 (Compound 20) is a PRMT5 inhibitor with antitumour effects. PRMT5, a protein arginine methyltransferase, is a novel anti-tumour target associated with epigenetic modifications. |