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Search Results for " prmt5 "

20

Compounds

Cat No. Product Name Synonyms Targets
T39008 PRMT5-IN-4 PRMT5-IN-4
PRMT5-IN-4 (compound AAA-1) is a PRMT5 inhibitor.
T39809 PRMT5-IN-14 PRMT5-IN-14
PRMT5-IN-14 is a PRMT5 inhibitor to treat cancer, sickle cell, and hereditary persistence of foetal hemoglobin (HPFH) mutations.
T40197 PRMT5-IN-11 PRMT5-IN-11
PRMT5-IN-11 demonstrates potent structure-dependent inhibition against the protein methyltransferase PRMT5:MEP50 complex at submicromolar concentrations.
T40202 PRMT5-IN-12 PRMT5-IN-12
PRMT5-IN-12 shows remarkable inhibitory activity on PRMT5 .
T39934 PRMT5-IN-13 PRMT5-IN-13
PRMT5-IN-13 is a selective inhibitor of protein arginine methyltransferase 5 (prmt5) .
T39993 PRMT5-IN-15 PRMT5-IN-15
PRMT5-IN-15 is a PRMT5 inhibitor with an IC 50 value of 0.84 nM.
T40313 PRMT5-IN-9 PRMT5-IN-9
PRMT5-IN-9 is a novel PRMT5 inhibitor for treating cancer, with an IC 50 of 0.01 μM.
T16577 PRMT5-IN-2 Histone Methyltransferase
PRMT5-IN-2 is an inhibitor of protein arginine methyltransferase 5.
T12541 PRMT5-IN-1 Histone Methyltransferase
PRMT5-IN-1 is a covalent inhibitor of protein arginine methyltransferase 5 (PRMT5)(IC50 of 11 nM for PRMT5/MEP50).
T69430 PRMT5-IN-C17
PRMT5-IN-C17 is a novel potent, selective, and cell active protein arginine methyltransferase 5 (PRMT5) inhibitor.
T62683 PRMT5-IN-3
PRMT5-IN-3 is a PRMT5 inhibitor.PRMT5-IN-3 is a combined DNA damaging agent that is synthetically lethal to tumor cells.
T63103 PRMT5-IN-17
PRMT5-IN-17 (Compound 6) is a PRMT5 inhibitor that exhibits antitumour activity. PRMT5, a protein arginine methyltransferase, is a novel anti-tumour target associated with epigenetic modifications.
T78152 PRMT5-IN-25 Histone Methyltransferase
PRMT5-IN-25 (compound 503) is a potent inhibitor of PRMT5, exhibiting an inhibition constant (K i) of 0.06 nM and demonstrating antiproliferative properties [1].
T63860 PRMT5-IN-18
PRMT5-IN-18 (Compound 002) is a potent inhibitor of PRMT5 and can be used in the study of PRMT5-mediated diseases, such as tumours.
T61986 PRMT5-IN-21
PRMT5-IN-21 (compound 1) is a potent inhibitor of cyclonucleoside PRMT5.
T60725 PRMT5-IN-10
PRMT5-IN-10 exhibits promising structure-dependent inhibitory effect on the protein methyltransferase PRMT5:MEP50 complex.
T76413 PRMT5-IN-22
PRMT5-IN-22 (compound 53), an inhibitor of protein arginine methyltransferase 5 (PRMT5), exhibits anti-tumor activity. As a protein arginine methyltransferase, PRMT5 represents a novel anti-tumor target associated with e...
T78172 PRMT5-IN-29 Histone Methyltransferase
PRMT5-IN-29 is a potent, orally active inhibitor of PRMT5, exhibiting an IC50 value of 1.5 μM, showing promise for use in advanced cancer research [1].
T79035 PRMT5-IN-28 Histone Methyltransferase
PRMT5-IN-28 (compound 36) serves as an inhibitor of the protein arginine methyltransferase 5 (PRMT5) enzyme, which is implicated in various cellular processes including gene transcription, mRNA splicing, DNA repair, prot...
T63138 PRMT5-IN-16
PRMT5-IN-16 (Compound 20) is a PRMT5 inhibitor with antitumour effects. PRMT5, a protein arginine methyltransferase, is a novel anti-tumour target associated with epigenetic modifications.
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