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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T68378 | PRMT4-IN-1 | Histone Methyltransferase | |
PRMT4-IN-1 is a selective inhibitor of PRMT4, demonstrating an IC50 value of 3.2 nM, and has been shown to reduce the relative viability of MCF7 cells [1]. | |||
T28996 | TP-064 | TP 064 | Histone Methyltransferase |
TP-064 is a potent and selective PRMT4 inhibitor. TP-064 includes inhibition of PRMT4 with IC50 < 10nM for methylation of H3 (1-25) and greater than 100-fold selectivity over other histone methyltransferases and non-epig... | |||
T27133 | DCLX069 | DCLX 069,DCLX-069 | Histone Methyltransferase |
DCLX069 is a potent and selective PRMT1 inhibitor. DCLX069 occupies the SAM binding pocket to exert the inhibitory effect. DCLX069 effectively blocks cell proliferation in breast cancer, liver cancer and acute myeloid le... | |||
T81399 | PRMT4-IN-2 | ||
PRMT4-IN-2 (compound 55) acts as a pan-inhibitor across various protein arginine methyltransferase (PRMT) isoforms, exhibiting inhibitory potencies with IC50 values of 92 nM for PRMT4, 436 nM for PRMT6, 460 nM for PRMT1,... | |||
T79355 | PRMT4-IN-3 | Histone Methyltransferase | |
PRMT4-IN-3 (compound 56) serves as a potent class I protein arginine methyltransferase (PRMT) inhibitor, specifically targeting PRMT4 with an IC50 value of 37 nM, and displays weaker inhibition toward PRMT6, with an IC50... |