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Search Results for " ppar-δ "

11

Compounds

Cat No. Product Name Synonyms Targets
T39516 Bocidelpar PPAR
Bocidelpar is a modulator of PPARδ with an EC50 of 7.80 nM and improves mitochondrial biogenesis and function in Duchenne Muscular Dystrophy muscle cells.
T15567 Imiglitazar TAK-559 PPAR
Imiglitazar (TAK559) is a potent PPAR-β/δ receptor agonist with hypoglycemic effects.
T15575 Indeglitazar PPM 204 PPAR
Indeglitazar (PPM 204) is orally available pan-agonist of PPAR (PPAR subtypes alpha (α), delta (δ), and gamma (γ)).
T4408 Elafibranor GFT505 PPAR
Elafibranor (GFT505) is an agonist of the peroxisome proliferator-activated receptor-α (PPAR-α) and peroxisome proliferator-activated receptor-δ (PPAR-δ) with EC50 values of 45 and 175 nM, respectively.
T4628 Seladelpar MBX 8025 PPAR
Seladelpar (MBX 8025) has been used in trials studying the treatment of Hyperlipidemia.
T12528 Pparδ agonist 1 Others
Pparδ agonist 1 is an agonist of PPAR-δ(EC50 of 5.06 nM).
T26182 Seladelpar lysine MBX-8025 lysine dihydrate,MBX-8025 Lysine,MBX 8025 Lysine MBX8025 Lysine
Seladelpar lysine, a selective PPAR-δ agonist, is used for the therapy of Homozygous Familial Hypercholesterolemia (HoFH).
T70886 PT-S58
PT-S58 is a PPAR β/δ full antagonist, and a derivative of GSK0660. PT-S58 has a three-fold higher affinity for the receptor than GSK0660 and is a potent inhibitor of agonist-induced target gene expression. PT-S58 are eff...
T37829 CAY10573
The peroxisome proliferator-activated receptors (PPARs) are lipid-activated transcription factors often used as drug targets for the treatment of metabolic disorders. CAY10573 is a PPAR agonist that displays potent bindi...
T79454 Anti-NASH agent 1 PPAR
Anti-NASH Agent 1 (Compound 3d), derived from Elafibranor, serves as a strong PPAR-α/δ agonist aimed at treating nonalcoholic steatohepatitis (NASH). At dosages of 3-10 mg/kg over four weeks, this compound ameliorates hy...
T35813 CAY10592
Peroxisome proliferator-activated receptors (PPARs) α, δ, γ are ligand-activated nuclear transcription factors involved in the regulation of energy homeostasis as well as insulin sensitivity and glucose metabolism. Pharm...
TargetMol