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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T64058 | PLK1/BRD4-IN-1 | ||
PLK1/BRD4-IN-1 (9b) is an orally active dual inhibitor of PLK1 (IC50: 22 nM) and BRD4 (IC50: 109 nM). It has been shown to have good anti-tumour effects in vivo. | |||
T79065 | WWL0245 | Epigenetic Reader Domain | |
WWL0245 is a potent and selective BRD4-targeting PROTAC that exhibits sub-nanomolar degradation efficiency (DC50 < 1 nM) for BRD4 over BRD2/3 and PLK1 (DC50 > 1 μM). It demonstrates pronounced selective cytotoxicity in B... |