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Search Results for " pkc412 "

5

Compounds

Cat No. Product Name Synonyms Targets
T3211 Midostaurin N-Benzoylstaurosporine,PKC412,CGP41231,CGP 41251 Others , PKC
PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor. Midostaurin inhibits protein kinase C alpha (PKCalpha), vascular endothelial growth factor receptor 2 (VEGFR2), c-kit, platel...
T12036 Midostaurin-D5 PKC412-D5,CGP 41251-D5 Others
Midostaurin-D5 is a deuterium labeled Midostaurin.
T12280 O-Desmethyl Midostaurin CGP62221,O-Desmethyl PKC412 Others
O-Desmethyl Midostaurin is the active Midostaurin metabolite via cytochrome P450 liver enzyme metabolism.
T12610L 3-Hydroxy Midostaurin CGP52421 FLT
3-Hydroxy Midostaurin (CGP 52421), a PKC412 metabolite, inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation with IC50 values of roughly 132 nM in culture medium and 9.8 μM in plasma. Though less selective, it ...
T19119 3-Hydroxy Midostaurin-D5 CGP52421-D5 Others
3-Hydroxy Midostaurin-D5 (CGP52421-D5) is a deuterium-labeled 3-Hydroxy Midostaurin which is a metabolite of PKC412. PKC412 effectively inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation (IC50s: 132 nM and 9....
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