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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T23498 | UNC3230 | UNC 3230 | Others |
UNC3230 is a potent, selective and ATP-competitive PIP5K1C inhibitor with an IC50 of ~41 nM. UNC3230(UNC 3230) also inhibits PIP4K2C. | |||
T70683 | NA 382 | ||
NA 382 is a staurosporine derivative that inhibits multidrug resistance. | |||
T15375 | Inavolisib | GDC-0077,RG6114 | Apoptosis , PI3K |
Inavolisib (GDC-0077) is an orally available and selective inhibitor of PI3Kα (IC50=0.038 nM). Inavolisib is more selective for mutant versus wild-type PI3Kα. Inavolisib exerts its activity by binding to the ATP binding ... | |||
TP1977 | 187-1, N-WASP inhibitor | ||
Inhibits neural Wiskott-Aldrich syndrome protein (N-WASP) by stabilizing the autoinhibited state of the protein. Blocks phosphatidylinositol 4,5-bisphosphate (PIP2)-stimulated actin assembly (IC50 ~ 2 μM) but does not di... | |||
TP1948 | PBP10 | PBP 10 | |
Selective formyl peptide receptor 2 (FPR2) antagonist; cell permeable. Selectively inhibits FPR2-mediated NADPH oxidase activity but has no effect on FPR1 signaling in neutrophils. Displays PIP2 binding activity in vitro... | |||
T36938 | PtdIns-(3)-P1 (1,2-dioctanoyl) (sodium salt) | PtdIns-(3)-P1 (1,2-dioctanoyl) (sodium salt) | |
The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3)-P1 (1,2-dio... | |||
T75777 | 187-1, N-WASP inhibitor TFA | ||
187-1, N-WASP Inhibitor TFA, a 14-amino acid cyclic peptide, serves as an allosteric inhibitor of the neural Wiskott-Aldrich syndrome protein (N-WASP). This compound effectively suppresses actin assembly triggered by pho... | |||
T37030 | PtdIns-(4)-P1 (1,2-dioctanoyl) (ammonium salt) | PtdIns-(4)-P1 (1,2-dioctanoyl) (ammonium salt) | |
The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(4)-P1 (1,2-dio... | |||
T36937 | PtdIns-(1,2-dioctanoyl) (sodium salt) | ||
The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(1,2-dioctanoyl... |