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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T16670 | PS210 | PDK | |
PS210 is a potent and selective activator of PDK1 (Kd: 3 μM), specifically targeting the PIF-binding pocket of PDK1, without acting against other protein kinases such as S6K, PKB/Akt, or GSK3. Its prodrug, PS423, serves ... | |||
T3163 | PS 48 | PDK | |
PS 48 has been shown to be a PKB Kinase (PDK1) activator (Kd: 10.3 μM). This compound selectively binds to the PIF-binding pocket of PKB Kinase (PDK1). | |||
T24676 | PS423 | PS210AM,PS 210 AM,PS 423,PS210-AM,PS-423 | |
PS423 is a substrate-selective protein kinase PDK1 inhibitor that acts by binding to the PIF-pocket allosteric docking site. | |||
T16671 | PS315 | PKC | |
PS315 inhibits the full-length and catalytic domain constructs of PKCζ (IC50=10 μM) and PKCη (IC50=30 μM). PS315 has anti-cancer activity. PS315 is a derivative of PS48 and is an allosteric PKC inhibitor by binding to th... |