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Cat No. | Product Name | Synonyms | Targets |
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T72950 | 15-PGDH-IN-1 | ||
15-PGDH-IN-1 is an orally active, potent inhibitor of 15-PGDH, exhibiting significant inhibitory activity against recombinant human 15-PGDH with an IC50 value of 3 nM. This compound is utilized in the research of tissue ... | |||
T38163 | ML-148 | Dehydrogenase | |
ML-148 is a selective inhibitor of 15-hydroxy prostaglandin dehydrogenase (15-PGDH, IC50 = 56 nM). ML-148 can be used to profile across a panel of related dehydrogenase or reductase enzymes and in studies about prostagla... | |||
T2121 | SW033291 | Dehydrogenase | |
SW033291 is a small-molecule inhibitor of 15-PGDH (Ki=0.1 nM) that increases prostaglandin PGE2 levels in bone marrow and other tissues. | |||
T26956 | CAY10397 | ||
CAY10397, a selective inhibitor of 15-hydroxy PGDH, significantly suppresses endogenous 11-oxo-ETE production with a corresponding increase in 11(R)-HETE. | |||
T37840 | 20-hydroxy Prostaglandin F2α | 20-hydroxy Prostaglandin F2α | |
20-hydroxy Prostaglandin F2α (20-hydroxy PGF2α) is the ω-oxidation product of PGF2α. Cultured type II alveolar cells from pregnant rabbits metabolize exogenous PGF2α via microsomal cytochrome P450 ω-oxidation, producing ... | |||
T37990 | 15-keto Prostaglandin F1α | 15-keto Prostaglandin F1α | |
15-keto PGF1α is the initial metabolite of PGF1α via 15-hydroxy PGDH. In mammals, oxidation of C-15 markedly attenuates receptor binding and activity. In fish, the 15-keto compounds serve as post-ovulatory pheromones and... | |||
T35708 | N-acetyl-5-Aminosalicylic Acid | ||
N-acetyl-5-Aminosalicylic acid is a metabolite of the anti-inflammatory agent 5-aminosalicylic acid and its prodrug form, sulfasalazine . It is formed in the liver, intestinal lumen, and colonic epithelial cells via N-ac... |
Cat No. | Product Name | Species | Expression System |
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TMPY-01264 | 15-PGDH Protein, Human, Recombinant (His) | Human | E. coli |
15-PGDH Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 29.7 kDa and the accession number is P15428-1. | |||
TMPY-02801 | PHGDH Protein, Human, Recombinant (His) | Human | E. coli |
PHGDH is a member of the D-isomer specific 2-hydroxyacid dehydrogenase family. This new family consists of D-isomer-stereospecific enzymes. The conserved residues in this family appear to be the residues involved in the ... | |||
TMPY-02273 | 15-PGDH Protein, Mouse, Recombinant (His) | Mouse | E. coli |
15-PGDH Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 30.6 kDa and the accession number is Q8VCC1. |