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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2050 | PF-06447475 | LRRK2 | |
PF-06447475 is a highly effective, specific, brain penetrant LRRK2 inhibitor with IC0 of 3/11 nM for wild type LRRK2 and G2019S LRRK2 respectively. | |||
T7729 | PF-06454589 | LRRK2 | |
PF-06454589 is a potent inhibitor of LRRK2. | |||
T73846 | PF-06456384 trihydrochloride | ||
PF-06447475 trihydrochloride is a potent, selective LRRK2 kinase inhibitor that demonstrates excellent brain penetration, exhibiting IC50 values of 3 nM for wild-type LRRK2 and 11 nM for G2019S LRRK2 variants. It holds p... |