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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8659 | K-Ras-PDEδ-IN-1 | PDE | |
K-Ras-PDEδ-IN-1 is a potent inhibitor of competitive K-Ras-PDEδ.It binds to the farnesyl binding pocket of PDEδ(Kd of 8 nM). | |||
T32419 | KRAS4b-PDEδ stabilizer C19 | ||
KRAS4b-PDEδ stabilizer C19 is a stabilizer of the KRAS4b-PDEδ complex which decreases the proliferation of colorectal cancer cells, and increases apoptosis via decreased activation of oncogenic KRAS4b signaling. | |||
T6462 | Deltarasin | PDE , Ras | |
Deltarasin is a small molecular inhibitor of KRAS-PDEδ interaction with Kd of 38 nM for binding to purified PDEδ. | |||
T10994 | Deltasonamide 2 | PDE | |
Deltasonamide 2 is a competitive, high affinity PDEδ inhibitor with a Kd of ~385 pM. | |||
T10994L | Deltasonamide 2 hydrochloride | Deltasonamide 2 hydrochloride (2088485-34-9 free base) | PDE |
Deltasonamide 2 hydrochloride is a competitive high-affinity PDEδ inhibitor with a Kd of approximately 385 pM. | |||
T10994L2 | Deltasonamide 2 (TFA) | PDE | |
Deltasonamide 2 TFA is competitive, high affinity PDEδ inhibitor with a Kd of ~385 pM. | |||
T23977 | Deltazinone | ||
Deltazinone is a selective PDEδ inhibitor. Deltazinone exhibits less unspecific cytotoxicity and demonstrates a high correlation with the phenotypic effect of PDEδ knockdown in a set of human pancreatic cancer cell line... | |||
T38920 | Atrovastatin-PEG3-FITC | Atrovastatin-PEG3-FITC | |
Atrovastatin-PEG3-FITC (compound S31) functions as a ligand in fluorescence anisotropy assay. Its primary role is as a KRAS-PDEδ interaction inhibitor. | |||
T70646 | Deltarasin HCl | ||
Deltarasin is a high affinity PDEδ-KRAS interaction inhibitor. Deltarasin can inhibit KRAS-PDEδ interactions by binding to a hydrophobic pocket on PDEδ, resulting in the impairment of cell growth, KRAS activity, and RAS/... | |||
T71717 | KRAS4b-IN-D14 | ||
KRAS4b-IN-D14 is a specific inhibitor of oncogenic KRAS4b signaling which stabilizes the KRAS4b-PDEδ complex and remarkably decreases tumor size and triggered apoptosis of tumor cells. |