4
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T7504 | Necrostatin 2 racemate | Necrostatin-2 racemate | RIP kinase |
Necrostatin 2 racemate (Necrostatin-2 racemate) is an potent and specific inhibitor of RIPK1. | |||
T12203L | Necrostatin 2 | Others | |
Necrostatin 2 is an effective necroptosis inhibitor. Necrostatin 2 is also a RIPK1 inhibitor. EC50 for inhibition of necroptosis in FADD-deficient Jurkat T cells treated with TNF-α is 0.05 μM. | |||
T12203 | Necrostatin 2 S enantiomer | Others | |
Necrostatin 2 S enantiomer is the S enantiomer of Necrostatin 2 | |||
T9095 | Necrostatin-34 | 2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1,4 | RIP kinase |
Necrostatin-34 (2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1,4) is a RIPK1 kinase inhibitor, stabilizing RIPK1 kinase in an inactive conformation by occupying a distinct binding pocket in the kinase domain. |