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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T39292 | NS2 (114-121), Influenza | NS2 (114-121), Influenza | |
NS2 (114-121), Influenza, is a fragment derived from the nonstructural protein 2 (NS2) of the influenza virus. This compound serves as an epitope for influenza research and can be utilized to study the CD8+ cytotoxic T l... | |||
T16732 | Reproxalap | NS-2,ADX-102 | Others |
Reproxalap (NS-2) covalently binds aldehydes including malondialdehyde and 4-hydroxynonenal. Reproxalap is a reactive aldehyde species sequestering agent for the treatment of the dry eye. | |||
T62437 | NS2B/NS3-IN-6 | ||
NS2B/NS3-IN-6 (Compound 1a) is a variant of the DENV and ZIKV NS2B/NS3 protease inhibitor with IC50 values of 2.23 μM and 25.2 μM for the NS2B/NS3 protease of ZIKV and DENV, respectively. | |||
T81641 | NS2B-NS3pro-IN-2 | Virus Protease | |
Compound 11, also known as NS2B-NS3pro-IN-2, functions as an inhibitor of the Zika Virus NS2B-NS3 protease and exhibits antiviral properties at a concentration of 50 μM [1]. | |||
T78653 | NS2B/NS3-IN-3 hydrochloride | Virus Protease | |
NS2B/NS3-IN-3 hydrochloride is a Flavivirus NS2B-NS3 protease inhibitor [1]. | |||
T72887 | NS2B/NS3-IN-7 | ||
NS2B/NS3-IN-7 is a highly potent inhibitor of the Zika virus NS2B-NS3 protease, possessing a Ki value of 2.33 nM. It effectively reduces the number of ZIKV-infected cells. | |||
T60881 | NS2B/NS3-IN-3 | ||
NS2B/NS3-IN-3 (Compd 66) is an inhibitor of Flavivirus NS2B-NS3 protease [1] . | |||
T62932 | NS2B/NS3-IN-2 | ||
NS2B/NS3-IN-2 is a potent, covalent inhibitor of dengue virus (DENV) NS2B/NS3 (IC50: 6.0 nM, Ki: 0.66 μM). NS2B/NS3-IN-2 significantly increases cell viability and is not cytotoxic. | |||
T81642 | NS2B-NS3pro-IN-1 | Virus Protease | |
NS2B-NS3pro-IN-1, a potent Zika Virus NS2B-NS3 protease inhibitor, exhibits an EC50 of 50 μM and is significant in the ZIKV replication cycle [1]. | |||
T81114 | Spns2-IN-1 | LPL Receptor | |
Spns2-IN-1 is a potent Spns2 inhibitor, effectively impeding Spns2-dependent S1P transport with an IC50 value of 1.4±0.3 μM, crucial for modulating the immune response [1]. | |||
T62104 | NS2B/NS3-IN-5 | ||
NS2B/NS3-IN-5 (Compound 25b) is a variant of the DENV2 and ZIKV NS2B/NS3 protease inhibitor with IC50 values of 0.67 μM and 4.38 μM for the NS2B/NS3 protease of ZIKV and DENV2, respectively. | |||
T60458 | NS2B/NS3-IN-4 | ||
Compound 34e (NS2B/NS3-IN-4) is an allosteric inhibitor of the DENV2 and ZIKV NS2B/NS3 proteases, exhibiting IC50 values of 0.69 µM for DENV2 and 1.04 µM for ZIKV NS2B/NS3 proteases [1]. |