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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T81661 | NNMT-IN-4 | ||
NNMT-IN-4 (compound 38) is a selective, uncompetitive inhibitor of nicotinamide N-methyltransferase (NNMT) with in vitro biochemical and cell-based assay IC50 values of 42 nM and 38 nM, respectively. It demonstrates favo... | |||
T63493 | NNMT-IN-2 | ||
NNMT-IN-2 is a very potent inhibitor of NNMT (IC50: 3.7 nM). | |||
T64189 | NNMT-IN-3 | ||
NNMT-IN-3 (compound 14) is a potent and selective inhibitor of nicotinamide N-methyltransferase (NNMT) with IC50 values of 1.1 nM and 0.4 μM in cell-free and cell-based assays, respectively. nNMT-IN-3 can be used in stud... | |||
T8760 | NNMTi | 5-Amino-1-methylquinolinium | Others |
NNMTi (5-Amino-1-methylquinolinium) is a substrate site-targeting, selective nicotinamide N-methyltransferase (NNMT) inhibitor (IC50 = 1.2 μM; 50 μM SAM, 100 μM NCA) that reduces 3T3-L1 lipogenesis (EC50 = 30μM) and adip... | |||
T8106 | JBSNF-000088 | JBSNF000088 | Others |
JBSNF-000088 is an Nicotinamide N-methyltransferase (NNMT)inhibitor. It is used for the treatment of metabolic disorders. | |||
T72947 | JBSNF-000028 | JBSNF-000028 free base | Others |
JBSNF-000028 is an orally active and potent nicotinamide N-methyltransferase (NNMT) inhibitor with inhibitory effects on human NNMT (hNNMT), monkey NNMT (mkNNMT), and mouse NNMT (mNNMT) with IC50s of 0.033 μM, 0.19 μM, a... | |||
T36802L | Bisubstrate Inhibitor 78 HCl | Bisubstrate Inhibitor 78 HCl(2368247-39-4 Free base) | Others |
Bisubstrate Inhibitor 78 HCl is an NNMT inhibitor (IC50 = 1.41 μM) with potential anticancer activity, inhibiting the proliferation of HSC-2 oral cancer cells at 100 μM. | |||
T78163 | JBSNF-000028 TFA | Others | |
JBSNF-000028 TFA, a nicotinamide N-methyltransferase (NNMT) inhibitor, exhibits oral activity with inhibitory concentration 50 (IC50) values of 0.033 μM, 0.19 μM, and 0.21 μM for human NNMT (hNNMT), monkey NNMT (mkNNMT),... | |||
T82011 | JBSNF-000028 free base | ||
JBSNF-000028 is an orally active inhibitor of nicotinamide N-methyltransferase (NNMT) demonstrating inhibitory concentration (IC50) values of 0.033 µM for human NNMT (hNNMT), 0.19 µM for monkey NNMT (mkNNMT), and 0.21 µM... | |||
T78164 | JBSNF-000028 hydrochloride | Others | |
JBSNF-000028 hydrochloride is a potent inhibitor of nicotinamide N-methyltransferase (NNMT) with IC50 values of 0.033 μM for human NNMT (hNNMT), 0.19 μM for monkey NNMT (mkNNMT), and 0.21 μM for mouse NNMT (mNNMT). This ... | |||
T71922 | MS2734 | ||
MS2734 is a novel Bisubstrate Inhibitor of Nicotinamide N-Methyltransferase (NNMT). | |||
T36802 | Bisubstrate Inhibitor 78 | ||
Bisubstrate inhibitor 78 is an inhibitor of nicotinamide N-methyltransferase (NNMT; IC50= 1.41 μM).1It binds the NNMT active site in the binding pockets for the NNMT substrates S-adenosyl-L-methionine (SAM) and nicotinam... |