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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T62902 | NDI-034858 | TAK-279,NDI-03485 | IL Receptor , Tyrosine Kinases |
NDI-034858 (TAK-279) is a tyrosine kinase 2 (TYK2) inhibitor (Kd<200 pM) that targets the JH2 structural domain of Tyk2 for the treatment of autoimmune diseases caused by aberrant expression of IL12 and IL23. |