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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T35922 | NAADP (sodium salt) | ||
Nicotinic acid adenine dinucleotide phosphate (NAADP) is a secondary messenger that induces calcium mobilization. It induces calcium release from endosomes and lysosomes via two-pore channel 2 (TPC2) and TPC1, which then... | |||
T83801 | ε-NAADP+ sodium | Etheno-NAADP,β-Nicotinic Acid-1,N6-Ethenoadenine dinucleotide phosphate,Nicotinic Acid adenine dinucleotide phosphate | |
ε-NAADP+ is a fluorescent derivative of NAADP, known for inducing calcium mobilization. It effectively induces calcium release in sea urchin egg homogenates with an EC50 of 5 µM. The compound exhibits excitation and emis... | |||
T23049 | NAADP tetrasodium salt | Others | |
Ca2+ mobilizing agent | |||
T12205 | Ned 19 | Calcium Channel | |
Ned 19 is a selective membrane-permeant non competitive antagonist of NAADP and strongly inhibits tumor growth and vascularization as well as lung metastases in mice. | |||
T22670 | Cis-Ned 19 | Others | |
nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist | |||
T63649 | Ned-K | ||
Ned-K is a nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist that exhibits an inhibitory effect on myocardial ischemia and reperfusion (sIR)-induced calcium oscillations. | |||
T12205L | Trans-Ned 19 | Calcium Channel | |
trans-Ned 19 is a NAADP antagonist and TPC blocker and inhibits the calcium signal in human umbilical vein endothelial cells and the rat aorta relaxation in response to low histamine concentrations. | |||
T36805 | TPC2-A1-N | TPC2-A1-N | |
TPC2-A1-N is a novel, lipophilic, membrane permeable isoform-selective small molecule agonist of two-pore channel 2 (TPC2). TPC2-A1-N plays its role by mimicking the physiological actions of NAADP and PI(3,5)P2 through i... |