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Search Results for " naadp "

8

Compounds

Cat No. Product Name Synonyms Targets
T35922 NAADP (sodium salt)
Nicotinic acid adenine dinucleotide phosphate (NAADP) is a secondary messenger that induces calcium mobilization. It induces calcium release from endosomes and lysosomes via two-pore channel 2 (TPC2) and TPC1, which then...
T83801 ε-NAADP+ sodium Etheno-NAADP,β-Nicotinic Acid-1,N6-Ethenoadenine dinucleotide phosphate,Nicotinic Acid adenine dinucleotide phosphate
ε-NAADP+ is a fluorescent derivative of NAADP, known for inducing calcium mobilization. It effectively induces calcium release in sea urchin egg homogenates with an EC50 of 5 µM. The compound exhibits excitation and emis...
T23049 NAADP tetrasodium salt Others
Ca2+ mobilizing agent
T12205 Ned 19 Calcium Channel
Ned 19 is a selective membrane-permeant non competitive antagonist of NAADP and strongly inhibits tumor growth and vascularization as well as lung metastases in mice.
T22670 Cis-Ned 19 Others
nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist
T63649 Ned-K
Ned-K is a nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist that exhibits an inhibitory effect on myocardial ischemia and reperfusion (sIR)-induced calcium oscillations.
T12205L Trans-Ned 19 Calcium Channel
trans-Ned 19 is a NAADP antagonist and TPC blocker and inhibits the calcium signal in human umbilical vein endothelial cells and the rat aorta relaxation in response to low histamine concentrations.
T36805 TPC2-A1-N TPC2-A1-N
TPC2-A1-N is a novel, lipophilic, membrane permeable isoform-selective small molecule agonist of two-pore channel 2 (TPC2). TPC2-A1-N plays its role by mimicking the physiological actions of NAADP and PI(3,5)P2 through i...
TargetMol