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Search Results for " msc2504877 "

2

Compounds

Cat No. Product Name Synonyms Targets
T60098 MSC2504877 3-(4-(2-Hydroxypropan-2-yl)phenyl)-6-methylpyrrolo[1,2-a]pyrazin-1(2H)-one Others
MSC2504877 is an inhibitor of tankyrase and enhances the effects of clinical CDK4/6 inhibitors. MSC2504877 suppresses the upregulation of Cyclin D2 and Cyclin E2 caused by palbociclib and enhances the suppression of phos...
T79026 Tankyrase-IN-5 PARP
Tankyrase-IN-5 (Compound 30f), structurally related to MSC2504877, effectively inhibits tankyrase isoforms TNKS1 and TNKS2, with half-maximal inhibitory concentrations (IC50s) of 2.3 nM and 7.9 nM, respectively [1].
TargetMol