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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6598 | MPEP | GluR | |
MPEP is a selective mGlu5 receptor antagonist with IC50 of 36 nM, exhibits no appreciable activity at mGlu1b/2/3/4a/7b/8a/6 receptors. | |||
T2497 | MPEP hydrochloride | GluR | |
MPEP hydrochloride is an effective and highly specific non-competitive antagonist at the mGlu5 receptor subtype (IC50: 36 nM). | |||
T71975 | 5-MPEP | ||
5-MPEP is a neutral allosteric site ligand of the metabotropic glutamate receptor subtype 5 (mGlu5), blocking the effects of both the allosteric antagonist MPEP and potentiator CDPPB. | |||
T71150 | Incadronic acid | ||
Incadronate, also known as Cimadronate and YM-175, is a bone resorption inhibitor. Incadronate disodium inhibits macrophage migration to site of inflammation in vivo and proliferation and causes apoptosis in cancer cell... | |||
T64442 | MMPEP | ||
MMPEP is both a selective non-competitive mGlu5 receptor antagonist with IC50 value of 36 nM and a mGlu4 receptor positive allosteric modulator. | |||
T25769 | M-5MPEP | ||
M-5MPEP is a mGlu5 antagonist. | |||
T8862 | ML 254 | GluR | |
ML254 competitively interacts with the MPEP allosteric binding site. ML254 is highly selective for mGlu5 versus other mGlu receptors, has a clean ancillary Ricerca profile, and suitable dystrophia myotonica protein kinas... | |||
T23509 | VU 0285683 | GluR | |
VU 0285683 is a specific negative allosteric modulator of mGluR5 with a high affinity for the MPEP binding site. VU 0285683 shows anxiolytic-like activity. |