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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6894 | ML264 | CID-51003603 | DNA/RNA Synthesis , KLF |
ML264 (CID-51003603) is a selective kruppel-like factor 5 (KLF5) inhibitor, which potently Inhibits growth of Colorectal Cancer. | |||
T9307 | (E)-3-(3,4-dichlorophenyl)-N-(2-(4-(methylsulfonyl)piperazin-1-yl)-2-oxoethyl)acrylamide | Others | |
SR18662 a.k.a. SR18662 is a KLF5 inhibitor based on the optimized structure of ML264. It inhibits the growth of colorectal cancer in vitro and in vivo. | |||
T22429 | SR18662 | DNA/RNA Synthesis | |
SR18662, an optimized compund based on ML264 that inhibits Krüppel-like factor 5 (KLF5) with IC50 of 4.4 nM, reduces the viability of multiple colorectal cancer cell lines and induces apoptosis. | |||
T29172 | YD277 | YD 277,YD-277 | |
YD277 is a small molecule derived from ML264, a KLF5 inhibitor that elicits cytotoxic effects in colon cancer cell lines. YD277 significantly induced G1 cell cycle arrest and apoptosis in MDA-MB-231 and MDA-MB-468 TNBC c... |