ml-128 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T6726	VU0361737	ML-128,VU 0361737	GluR
	VU0361737 (ML-128) is a specific positive allosteric modulator (PAM) of mGlu4 receptor.The EC50 of VU 0361737 is 240 nM for the human receptors. The EC50 of VU 0361737 is110 nM for rat receptors.It exhibits weak activity...		GluR
TN2281	Sinapaldehyde	trans-3,5-Dimethoxy-4-hydroxy cinnamaldehyde	Antibacterial
	Sinapaldehyde (trans-3,5-Dimethoxy-4-hydroxy cinnamaldehyde) is a natural product. Sinapaldehyde exhibits moderate antibacterial against Methicillin resistant S. aureus (MRSA) and E. coli with MIC values of 128 and 128 μ...		Antibacterial
T79004	ATP synthase inhibitor 2 TFA
	ATP Synthase Inhibitor 2 (Compound 22) TFA is a potent inhibitor of Pseudomonas aeruginosa ATP synthase with an IC50 value of 10 μg/mL. It effectively halts ATP synthesis in Pseudomonas aeruginosa at a concentration of 1...
T29175	YKAs3003	YKAs-3003
	YKAs3003, a potent inhibitor of pathogenic KAS III, displays minimal inhibitory concentration (MIC) values in the range 128-256 microg/mL against various bacteria.
T38917	Antibacterial agent 50
	Antibacterial agent 50 (example 47) is a compound that exhibits antibacterial activity. It shows minimum inhibitory concentration (MIC) values of 32, 64, and 128 mcg/mL against three strains of E. coli, namely NCTC 13351...
T61649	ATP synthase inhibitor 2
	ATP Synthase Inhibitor 2, a compound targeting Pseudomonas aeruginosa (PA) ATP synthase with an IC50 of 10 μg/mL, fully inhibits the ATP synthesis activity of PA at a concentration of 128 μg/mL [1].
T80276	Lynronne-3
	Lynronne-3, an antimicrobial peptide, demonstrates activity against Gram-positive bacteria, including multi-drug resistant (MDR) strains, with a minimum inhibitory concentration (MIC) ranging from 32-128 μg/mL for methic...
T75001	Antibacterial agent 128
	Antibacterial Agent 128, a siderophore analog-Ciprofloxacin (Ciprofloxacin) conjugate connected via a cleavable linker, demonstrates effective antibiotic properties. Specifically, it exhibits activity against P. aerugino...
T80091	Ranalexin
	Ranalexin, an antimicrobial peptide, demonstrates inhibition of S. aureus, E. coli, and P. aeruginosa, with respective minimum inhibitory concentrations (MICs) of 4, 32, and 128 μg/mL [1].
T61142	Antitubercular agent-17
	Antitubercular agent-17 (Compound 8a) is an efficacious antitubercular agent, demonstrating Minimum Inhibitory Concentration (MIC) values of 2 μg/ml against M. tuberculosis H37Rv, Spec. 192, and Spec 210, and 128 μg/ml a...
T61783	Antimicrobial agent-1
	Antimicrobial Agent-1 (compound 6C) shows strong activity (MIC = 2 μg/mL) against TolC mutant E. coli. Additionally, it synergistically interacts with Colistin to exhibit enhanced activity against Gram-negative bacteria....
T61143	Antitubercular agent-18
	Antitubercular agent-18 (Compound 9a) is an antitubercular agent that exhibits highly selective antimycobacterial effects, with minimum inhibitory concentration (MIC) values of 2 μg/ml against M. tuberculosis H37Rv, Spec...
T38321	A-39183A
	A-39183A is an active component of the A-39183 antibiotic complex produced by aerobic fermentation of Streptomyces NRRL 12049. It has activity against penicillin-resistant S. aureus 3055 and S. faecalis X66 (MICs = 32 an...
T80376	GP-2B
	GP-2B, an antimicrobial peptide, exhibits antibacterial activity against Gram-positive strains, with a minimum inhibitory concentration (MIC) ranging from 8 to 128 μg/mL for S. aureus and Enterococcus faecalis [1].
T37553	(-)-Mycousnine
	(-)-Mycousnine is a microbial metabolite and derivative of usnic acid originally isolated fromM. nawaethat has antibacterial and antifungal activities.1,2It is active against the Gram-positive bacteriaB. subtilis,K. rhiz...
T83921	IMCTA-C14 TFA
	IMCTA-C14, a detergent and derivative of the microbial metabolite 4-trehalosamine, exhibits a critical micelle concentration (CMC) of 0.11 mM and a hydrophilic-lipophilic balance (HLB) value of 9.72. It effectively extra...
TN1165	(Rac)-Myrislignan	1-(3,4-dimethoxyphenyl)-2-(4-allly-2,6-dimethoxyphenoxy)propan-1-ol,rac-myrislignan	Others
	1-(3,4-Dimethoxyphenyl)-2-(4-allly-2,6-dimethoxyphenoxy)propan-1-ol shows anti-staphylococcal activity against a total of five multidrug-resistant (MDR) and methicillin-resistant Staphylococcus aureus strains and the min...		Others
T36746	Leoidin
	Leoidin is a depsidone originally isolated from L. gangaleoides that has antibacterial and enzyme inhibitory activities.1,2,3 It is active against the bacteria E. faecalis, H. influenzae, M. catarrhalis, S. aureus, and S...
T35426	β-Defensin-1 (human) (trifluoroacetate salt)
	β-Defensin-1 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts.1It inhibits the growth ofB. adolescentis,L. acidophilus...