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Search Results for " mat2a "

20

Compounds

Cat No. Product Name Synonyms Targets
T11950 MAT2A inhibitor 2 Others , Methionine Adenosyltransferase (MAT)
MAT2A inhibitor 2 is an inhibitor of methionine adenosyltransferase 2A (MAT2A).
T9262 MAT2A inhibitor 4 Others , Methionine Adenosyltransferase (MAT)
MAT2A Inhibitor 4 acts as an inhibitor targeting the catalytic subunit of methionine S-adenosyltransferase-2 (MAT2A), offering potential utility in cancer research.
T73140 MAT2A-IN-9 Methionine Adenosyltransferase (MAT)
MAT2A-IN-9, a 2-oxoquinazoline derivative, is a potent MAT2A (methionine adenylyltransferase 2A) inhibitor.MAT2A-IN-9 has antitumor activity for the treatment of lymphomas and solid tumors.
T16013 MAT2A inhibitor 1 Others
MAT2A inhibitor 1 is an inhibitor of methionine adenosyltransferase 2A (MATA2) (IC50 < l00 nM).
T63975 MAT2A-IN-1
MAT2A-IN-1 is a potent inhibitor of MAT2A and is capable of proliferative activity in MTAP-deficient cancer cells. MAT2A is expressed at unusually high levels in several tumour types, including gastric, colon, liver and ...
T60903 MAT2A-IN-4
MAT2A-IN-4 can be used for the cancer research that is an inhibitor of methionine adenosyltransferase 2A (MAT2A)[1].
T62984 MAT2A-IN-2
MAT2A-IN-2 is a potent inhibitor of MAT2A. MAT2A-IN-2 has potential for cancer disease research.
T60668 MAT2A inhibitor 3
MAT2A inhibitor 3 can be used in the cancer research. MAT2A inhibitor 3 is a inhibitor of methionine adenosyltransferase 2A (MAT2A) with an IC 50 of <200 nM [1].
T79349 MAT2A-IN-11 Methionine Adenosyltransferase (MAT)
MAT2A Allosteric Inhibitor 1, also known as Compound 5, is a selective inhibitor of methionine adenosyltransferase (MAT) demonstrating potent activity with an IC50 value of 6.8 nM [1].
T62100 MAT2A-IN-6
MAT2A-IN-6 is a potent inhibitor of MAT2A. MAT2A-IN-6 reduces the proliferative activity of MTAP-deficient cancer cells. MAT2A-IN-6 has shown potential research value in cancer diseases.
T63603 MAT2A-IN-3
MAT2A-IN-3 is a potent inhibitor of MAT2A. MAT2A-IN-3 inhibits the proliferative activity of MTAP-deficient cancer cells. MAT2A-IN-3 has shown research potential for cancer diseases.
T61243 MAT2A-IN-5
MAT2A-IN-5, a potent inhibitor of MAT2A, effectively targets the abnormally elevated expression of MAT2A found in various tumor types such as gastric, colon, liver, and pancreatic cancers. By reducing the proliferative a...
T61672 MAT2A-IN-7
MAT2A-IN-7, a potent inhibitor of the enzyme MAT2A, demonstrates efficacy in targeting the abnormally elevated expression of MAT2A observed in gastric, colon, liver, and pancreatic cancers. Furthermore, MAT2A-IN-7 effect...
T78946 MAT2A-IN-10 Methionine Adenosyltransferase (MAT)
MAT2A-IN-10 (Compound 28), an orally active inhibitor of MAT2A, exhibits an IC50 of 26 nM and is utilized in cancer research [1].
T79350 MAT2A-IN-12 Methionine Adenosyltransferase (MAT)
MAT2A Allosteric Inhibitor 2 is a potent, selective inhibitor exhibiting an IC50 of 5 nM and demonstrates nanomolar efficacy (IC50 = 5 μM) in proliferation assays utilizing the MTAP -/- cell line [1].
T83973 MAT2A-IN-8
T11284 FIDAS-3 Others , Wnt/beta-catenin , Methionine Adenosyltransferase (MAT)
FIDAS-3, a stilbene derivative and potent Wnt inhibitor with an IC50 of 4.9 μM for methionine S-adenosyltransferase 2A (MAT2A), exhibits anticancer activities by effectively competing with S-adenosylmethionine (SAM) for ...
T11285 FIDAS-5 Others
FIDAS-5, a potent and orally active methionine S-adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 μM, competitively inhibits S-adenosylmethionine (SAM) binding to MAT2A. It exhibits anticancer activities.
T14141 AGI-24512 Others , Methionine Adenosyltransferase (MAT)
AGI-24512 is a inhibitor of methionine adenosyltransferase 2A (MATA2 ).It is useful for treatment of cancer and blocks growth of MTAP-deleted cancer cells in vitro.
T9050 AG-270 Others , Methionine Adenosyltransferase (MAT)
AG-270 is an allosteric and orally active inhibitor of MAT2A.
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TargetMol