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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6875 | Lesinurad | RDEA594 | OAT |
Lesinurad (RDEA594) is a selective inhibitor of uric acid reabsorption which is used in combination with other agents in the therapy of gout. Lesinurad has had a limited clinical use but has not been associated with seru... | |||
T21301 | Lesinurad sodium | Lesinurad,RDEA 594,RDEA-594,RDEA594 | |
UNC569, the first small-molecule MER inhibitor, inhibits Mer activation and downstream signaling through ERK1/2 and AKTwith. UNC569 shows efficacy against acute lymphoblastic leukemia in vitro and in vivo. | |||
T72632 | URAT1 inhibitor 4 | ||
URAT1 Inhibitor 4, derived from Lesinurad, is a potent, orally active inhibitor of URAT1 with an IC50 value of 7.56 μM, demonstrating greater in vivo urate-lowering efficacy than Lesinurad [1]. | |||
T79176 | URAT1 inhibitor 6 | ||
URAT1 inhibitor 6 (Compound 1h), with an IC50 of 35 nM for hURAT1, demonstrates 200-fold and 8-fold greater potency compared to Lesinurad and Benzbromarone, respectively. This compound is utilized in the study of inflamm... |