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Cat No. | Product Name | Synonyms | Targets |
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T69486 | BMD4503-2 | ||
BMD4503-2 is an LRP5/6-sclerostin interaction inhibitor. BMD4503-2 recovers the downregulated activity of the Wnt/β-catenin signaling pathway by competitively binding to the LRP5/6-sclerostin complex. | |||
T35551 | Gallocyanine | ||
Gallocyanine is a small molecule blue dye used to stain nuclei. It is known to inhibit Dickkopf-1 (Dkk1), an antagonist of the Wnt pathway. Gallocyanine can disrupt the interaction of Dkk1 with its receptor LRP5/6 (IC50 ... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPK-00740 | LRP-5 Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
A role for low-density lipoprotein-related receptor 5 (LRP5) in human bone was first established by the identification of genetic alterations that led to dramatic changes in bone mass. Shortly thereafter, mutations that ... | |||
TMPK-00739 | LRP-5 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
A role for low-density lipoprotein-related receptor 5 (LRP5) in human bone was first established by the identification of genetic alterations that led to dramatic changes in bone mass. Shortly thereafter, mutations that ... | |||
TMPY-06639 | LRP-5 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
LRP-5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.21 kDa and the accession number is O75197-1. | |||
TMPH-01223 | DKK2 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in... | |||
TMPJ-00156 | DKK1 Protein, Human, Recombinant (Avi & His), Biotinylated | Human | HEK293 Cells |
Dickkopf-related protein 1(DKK-1), is a member of the dickkopf family. DKK1 secreted proteins with two cysteine-rich domains separated by a linker region. It antagonizes canonical Wnt signaling by inhibiting LRP5/6 inter... |