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Search Results for " lrp5 "

2

Compounds

5

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T69486 BMD4503-2
BMD4503-2 is an LRP5/6-sclerostin interaction inhibitor. BMD4503-2 recovers the downregulated activity of the Wnt/β-catenin signaling pathway by competitively binding to the LRP5/6-sclerostin complex.
T35551 Gallocyanine
Gallocyanine is a small molecule blue dye used to stain nuclei. It is known to inhibit Dickkopf-1 (Dkk1), an antagonist of the Wnt pathway. Gallocyanine can disrupt the interaction of Dkk1 with its receptor LRP5/6 (IC50 ...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPK-00740 LRP-5 Protein, Human, Recombinant (mFc) Human HEK293 Cells
A role for low-density lipoprotein-related receptor 5 (LRP5) in human bone was first established by the identification of genetic alterations that led to dramatic changes in bone mass. Shortly thereafter, mutations that ...
TMPK-00739 LRP-5 Protein, Human, Recombinant (hFc) Human HEK293 Cells
A role for low-density lipoprotein-related receptor 5 (LRP5) in human bone was first established by the identification of genetic alterations that led to dramatic changes in bone mass. Shortly thereafter, mutations that ...
TMPY-06639 LRP-5 Protein, Human, Recombinant (His) Human HEK293 Cells
LRP-5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.21 kDa and the accession number is O75197-1.
TMPH-01223 DKK2 Protein, Human, Recombinant (His & SUMO) Human E. coli
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in...
TMPJ-00156 DKK1 Protein, Human, Recombinant (Avi & His), Biotinylated Human HEK293 Cells
Dickkopf-related protein 1(DKK-1), is a member of the dickkopf family. DKK1 secreted proteins with two cysteine-rich domains separated by a linker region. It antagonizes canonical Wnt signaling by inhibiting LRP5/6 inter...
TargetMol