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Search Results for " loxo-101 "

3

Compounds

Cat No. Product Name Synonyms Targets
T6880 Larotrectinib sulfate LOXO-101 sulfate,Larotrectinib (LOXO-101) sulfate,Larotrectinib,LOXO-101 (sulfate),ARRY-470,ARRY-470 (sulfate) Apoptosis , Trk receptor
Larotrectinib sulfate (LOXO-101 sulfate) is an oral active and specific ATP-competitive inhibitor of tropomyosin receptor kinases (TRK).
T5995 Larotrectinib LOXO-101,ARRY-470 Apoptosis , Trk receptor
Larotrectinib (LOXO-101) is an orally administered inhibitor of the TRK kinase and is highly selective only for the TRK family of receptors(IC50s = 2-20 nM).
T62531 TRK-IN-12
TRK-IN-12 (Compound 9e), a macrocyclic derivative, is a potent TRK inhibitor, with efficacy against TRK G595R (IC 50 = 13.1 nM). It demonstrates significant antiproliferative activity in the Ba/F3-LMNA-NTRK1 cell line (I...
TargetMol