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Search Results for " lly-283 "

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Compounds

Cat No. Product Name Synonyms Targets
T15767 LLY-283 Histone Methyltransferase
LLY-283 is a potent, selective and oral protein arginine methyltransferase 5 (PRMT5) inhibitor, with an IC50 of 22 nM and a Kd of 6 nM for PRMT5:MEP50 complex, and shows antitumor activity.
T22356 LLY-284 Others
LLY-284 is the diastereomer of LLY-283, which is a selective and potent SAM-competitive chemical probe for PRMT5. LLY-284 is much less active than LLY-283 and can be used as a negative control for LLY-283.
TargetMol