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Search Results for " indirubin-3'-monoxime "

4

Compounds

Cat No. Product Name Synonyms Targets
T5200 Indirubin-3'-monoxime Indirubin-3'-oxime GSK-3 , Lipoxygenase , CDK
Indirubin-3'-monoxime (Indirubin-3'-oxime) is a potent inhibitor of GSK3β (IC50: 22 nM) and also inhibits CDKs ( (IC50s: 100/180/250 nM for Cdk5/p35, Cdk1/cyclin B, Cdk2/cyclin E).
T9138 Indirubin-3′-oxime Indirubin-3'-monoxime GSK-3 , CDK , JNK
Indirubin-3′-oxime is an effective inhibitor of cyclin-dependent protein kinases, and may play an obligate role in neuronal apoptosis in Alzheimer's disease.
T11652 Indirubin-3'-monoxime-5-sulphonic acid Others
Indirubin-3'-monoxime-5-sulphonic acid is a potent and selective inhibitor of GSK-3β, CDK5, and CDK1 with IC50s of 80nM,5 nM, and 7 nM, respectively.
T10172 5-Iodo-indirubin-3'-monoxime GSK-3 , CDK
5-Iodo-indirubin-3'-monoxime is a potent GSK-3β, CDK5/P25 and CDK1/cyclin B inhibitor, competing with ATP for binding to the catalytic site of the kinase (IC50s: 9, 20 and 25 nM).
TargetMol