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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TQ0016 | NKP-1339 | IT-139,KP-1339 | DNA/RNA Synthesis |
NKP-1339 (IT-139) induces G2/M cell cycle arrest, blockage of DNA synthesis, and induction of apoptosis via the mitochondrial pathway. | |||
T72543 | BOLD-100 free base | NKP-1339 free base ; IT-139 free base ; KP-1339 free base,KP-1339 free base,NKP-1339 free base,IT-139 free base | |
BOLD-100 free base (NKP-1339; IT-139), a ruthenium-based anticancer agent, inhibits stress-induced GRP78 upregulation, thus disrupting endoplasmic reticulum (ER) homeostasis. This action induces ER stress and unfolded pr... |