il4 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T60920	PDE4-IN-8
	PDE4-IN-8 (Example 5) is a potent Phosphodiesterase 4 (PDE4) inhibitor. The IC50 value of PDE4-IN-8 for PDE4B2 is 0.93 nM. However, PDE4-IN-8 has little effect on IL13, IL4, and IFNy with IC50 values of 4.04 nM, 36.33 nM...
T60921	PF-07038124
	PF-07038124 is an inhibitor of PDE4. The IC50 value of PF-07038124 for PDE4B2 is 0.5 nM. PF-07038124 shows inhibitory activities against IFNγ, IL4, and IL-13 with IC50 values of 1.06, 4.1, and 125 nM, respectively [1].

Recombinant Proteins

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Expression System：

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Cat No.	Product Name	Species	Expression System
TMPJ-00035	IL-4 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	IL-4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 18 KDa and the accession number is P05112.
TMPJ-00387	IL-4R alpha Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Interleukin-4 receptor subunit alpha(IL-4RA), alos known as Soluble IL-4 receptor subunit alpha, belongs to the type I cytokine receptor family and type 4 subfamily. It expressed in both Th1 and Th2 cells. It functions a...
TMPJ-00034	IL-4 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	IL-4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 40-55 KDa and the accession number is P05112.
TMPK-00034	IL-4 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Interleukin-4, also known as IL4, is a secreted protein which belongs to the IL-4 / IL-13 family. Interleukin-4 / IL4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation.In t...
TMPK-00035	IL-4 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Interleukin-4, also known as IL4, is a secreted protein which belongs to the IL-4 / IL-13 family. Interleukin-4 / IL4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation.In t...
TMPK-00919	IL-4 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Interleukin-4, also known as IL4, is a secreted protein which belongs to the IL-4 / IL-13 family. Interleukin-4 / IL4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation.In t...
TMPY-01862	IL-4 Protein, Human, Recombinant	Human	E. coli
	IL-4 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.1 kDa and the accession number is P05112-1.
TMPY-02603	STAT6 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Signal transducer and activator of transcription 6 (STAT6) is a transcription factor that is activated by interleukin-4 (IL-4)-induced tyrosine phosphorylation and mediates most of the IL-4-induced gene expression. STAT6...
TMPJ-01341	CCL24 Protein, Mouse, Recombinant	Mouse	E. coli
	Mouse CCL24 is a secreted protein, which is a member of the CC chemokine subfamily. Mouse Ccl24 cDNA encodes a 119 amino acid residue precursor protein, shares approximately 58% amino acid sequence identity with human Cc...
TMPH-03116	IL-4R Protein, Pig, Recombinant (His)	Sus scrofa (Pig)	E. coli
	Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production a...
TMPJ-00270	IL-13RA1 Protein, Mouse, Recombinant (His & Avi), Biotinylated	Mouse	HEK293 Cells
	Interleukin-13 receptor subunit alpha-1(IL-13RA1), also known as NR4, belongs to the hemopoietin receptor family. Interleukin-13 receptor is a complex of IL4R, IL13RA1, and possibly other components. It interacts with TR...
TMPH-01676	Meteorin-like/METRNL Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Hormone induced following exercise or cold exposure that promotes energy expenditure. Induced either in the skeletal muscle after exercise or in adipose tissue following cold exposure and is present in the circulation. A...
TMPJ-01003	STAT5B Protein, Human, Recombinant (His)	Human	E. coli
	Signal Transducer and Activator of Transcription 5b (STAT5B) is a member of the STAT family of transcription factors. They are responsible for an array of cellular activities including regulating growth, survival, differ...
TMPH-01552	IRF1 Protein, Human, Recombinant (GST & His)	Human	Baculovirus Insect Cells
	Transcriptional regulator which displays a remarkable functional diversity in the regulation of cellular responses. Regulates transcription of IFN and IFN-inducible genes, host response to viral and bacterial infections,...