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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T32055 | Hemiasterlin | NSC 695242,NSC-695242,Milnamide B,NSC695242,(-)-Hemiasterlin | |
Hemiasterlin is a cytotoxic peptide that acts by inducing mitotic arrest and abnormal spindle formation. | |||
T39320 | Hemiasterlin derivative-1 | ||
Hemiasterlin Derivative-1, a derivative of hemiasterlin, is utilized in the synthesis of Antibody-Drug Conjugates (ADC). | |||
T69003 | E7974 | ||
E7974 is an analog of the sponge-derived anti-microtubule tripeptide hemiasterlin with antimitotic and potential antineoplastic activities. Hemiasterlin analog E7974 binds to the Vinca domain on tubulin, resulting in inh... | |||
T13073 | Taltobulin trifluoroacetate | HTI-286 trifluoroacetate,SPA-110 trifluoroacetate | Others |
Taltobulin trifluoroacetate is a synthetic analogue of the tripeptide hemiasterlin, is a potent agent of antimicrotubule that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. | |||
T13073L | Taltobulin hydrochloride (228266-40-8 free base) | SPA-110 hydrochloride,Taltobulin hydrochloride,HTI-286 hydrochloride | Others |
Taltobulin hydrochloride is a synthetic analogue of the tripeptide hemiasterlin, is a potent agent of antimicrotubule that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. | |||
T77864 | SC239 | ||
SC239 is a 2-aminophenyl hemiasterlin-based agent-linker suitable for antibody-drug conjugate (ADC) applications. It features a tubulin-targeting warhead, SC209, connected through a cleavable valine-citrulline p-aminoben... | |||
T75240 | Taltobulin hydrochloride | ||
Taltobulin hydrochloride (HTI-286 hydrochloride), a synthetic analogue of the tripeptide hemiasterlin, effectively bypasses P-glycoprotein-mediated resistance both in vitro and in vivo as a robust antimicrotubule agent. ... |