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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T78557 | HOIPIN-1 | JTP0819958 | NF-κB |
HOIPIN-1 (JTP0819958) is a selective and potent inhibitor of linear ubiquitin chain assembly complex (LUBAC) (IC50 >2.8 μM).HOIPIN-1 inhibits LUBAC-mediated NF-kB activation. | |||
T8951 | JTP 0819958 - HOIPIN-1 | IκB/IKK | |
JTP-0819958 is a selective linear ubiquitin chain assembly complex (LUBAC) inhibitor with an IC50 of 2.8 μM[1]. JTP-0819958 suppress LUBAC-mediated NF-kB activation in vitro[2]. | |||
T62826 | HOIPIN-8 | ||
HOIPIN-8 is a potent inhibitor of the linear ubiquitin chain assembly complex (LUBAC) (IC50: 11 nM). HOIPIN-8 is a derivative of HOIPIN-1 and inhibits petit-LUBAC 255-fold more than HOIPIN-1 and inhibits LUBAC and TNF-α-... |