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Search Results for " hif-1α-in-5 "

5

Compounds

Cat No. Product Name Synonyms Targets
T60532 HIF--IN-5
HIF--IN-5 is an inhibitor of HIF- with an IC 50 value of 24 nM in HEK293T cells that also inhibits the activity of MAO-A. HIF--IN-5 downregulates the mRNA expressions of VEGF and PDK1 under hypoxia. HIF--IN-5 has...
T74530 GEM-5
GEM-5, a gemcitabine-based conjugate incorporating a HIF- inhibitor (YC-1) (IC 50 =30 nM), notably suppresses HIF- expression while enhancing tumor suppressor p53 expression. It induces apoptosis in A2780 cells and c...
T69966 Roxadustat-d5
Roxadustat-d5 is intended for use as an internal standard for the quantification of roxadustat by GC- or LC-MS. Roxadustat is an inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PH; IC50s = 1.4, 1.26, and 1....
T36404 PRLX-93936
PRLX-93936 is an analog of erastin that has antitumor activity. It inhibits the hypoxia-inducible factor 1 (HIF-1) signaling pathway under hypoxic conditions (IC50 = 0.09 μM in a cell-based reporter assay). PRLX-93936 (1...
T36749 Herboxidiene
Herboxidiene is a polyketide originally isolated from S. chromofuscus that has diverse biological activities.[1],[2,][3],[4],[5] It inhibits growth of HeLa S3, SK-MEL-2, PC3, A549, and EBC-1 cells with GI50 values rangin...
TargetMol