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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8799 | (E/Z)-IT-603 | IT603 | Others , NF-κB |
(E/Z)-IT-603 is a cell-permeable c-Rel inhibitor (IC50: 3μM). IT-603 directly and reversibly binds to c-Rel to change its conformation and blocks its DNA binding and transcriptional activity. | |||
T9948 | NecroX-7 | LC-280126,LC28-0126,LC28 0126 | NADPH-oxidase |
NecroX-7 (LC-280126) is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor. NecroX-7 can be used as an antidote to acetaminophen toxicity. NecroX-7 exerts a protective effect by preventing ... | |||
T80759 | XY-52 | ||
XY-52 (Compound 32), an ST2 (Stimulation-2) inhibitor, exhibits IC50 values of 5.68 μM and 4.59 μM in the AlphaLISA and HEK-Blue assays, respectively. It promotes proinflammatory T-cell proliferation and diminishes plasm... | |||
T63484 | CS12192 | ||
CS12192 is a compound that improves survival and increases body weight and has potential for graft-versus-host disease (GVHD) research. | |||
T80857 | VLHDDLLEA | ||
VLHDDLLEA, a peptide extractable from the HLA-A*0201 MHC complex, is identifiable by HLA-A*0201-restricted cytotoxic T cells (CTLs). It serves as a research tool in studies of graft versus host disease (GvHD) [1]. | |||
T80597 | Dafsolimab | SPV-T3a | |
Dafsolimab (SPV-T3a), an IgG2a murine monoclonal antibody (anti-CD3), induces cell death by modulating and activating the CD3/T cell receptor complex and is utilized in research pertaining to graft-versus-host disease (G... | |||
T82331 | Gavilimomab | ABX-CBL | |
Gavilimomab (ABX-CBL), an IgM murine monoclonal antibody, targets CD147 on cell surfaces to induce complement-mediated cytotoxicity. It is utilized in the study of graft-versus-host disease (GVHD) [1]. | |||
T76911 | Asunercept | ||
Asunercept (APG101; CAN008), a soluble CD95-Fc fusion protein, selectively targets and binds to CD95L, effectively disrupting CD95/CD95L signaling. It is utilized in research for treating glioblastoma multiforme (GBM), m... |