5
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1894 | Idelalisib | GS-1101,CAL-101 | PI3K , Autophagy |
Idelalisib (GS-1101) is a small molecule inhibitor of the PI3K catalytic subunit p110δ (IC50: 2.5 nM). The selectivity for p110δ is 40- to 300-fold than p110α/β/γ. | |||
T8651 | CAL-101 | (S)-2-(1-(9H-Purin-6-ylamino)ethyl)-5-fluoro-3-phenylquinazolin-4(3H)-one,GS-1101,Idelalisib | PI3K |
CAL-101 (Idelalisib) is a selective inhibitor of p110δ(IC50 : 2.5 nM; in cell-free assays); shown to have 40- to 300-fold greater selectivity for p110δ than p110α/β/γ, and 400- to 4000-fold more selectivity to p110δ than... | |||
T16716 | Rabacfosadine | VDC-1101,GS-9219 | Others |
Rabacfosadine is a novel prodrug of the nucleotide analogue PMEG and is designed as a cytotoxic agent. | |||
T24702 | Rabacfosadine succinate | VDC-1101 succinate,GS-9219 succinate,VDC 1101 succinate VDC1101 succinate,GS-9219-01 | |
Rabacfosadine succinate is the acyclic nucleoside phosphonate PMEG double prodrug. | |||
T11610 | Idelalisib D5 | CAL-101 D5,GS-1101 D5 | PI3K |
Idelalisib D5, a version of Idelalisib marked with deuterium, is an orally bioavailable and highly selective inhibitor of p110δ. |