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Search Results for " gmb-475 "

3

Compounds

Cat No. Product Name Synonyms Targets
T8488 GMB-475 Bcr-Abl
GMB-475 is a BCR-ABL1 tyrosine kinase degrader based on PROTAC, overcoming BCR-ABL1-dependent drug resistance. GMB-475 targets BCR-ABL1 protein and recruits the E3 ligase Von Hippel Lindau (VHL).resulting in ubiquitinati...
T17927 (S,R,S)-AHPC TFA VH032-NH2 TFA,VHL ligand 1 TFA Others , Ligand for E3 Ligase
(S,R,S)-AHPC TFA (VHL ligand 1 TFA) (VH032-NH2 TFA) is a VH032-based ligand designed for von Hippel-Lindau (VHL) protein recruitment. This compound can be linked to protein ligands (e.g., BCR-ABL1) using a linker to crea...
T73941 PROTAC BCR-ABL1 ligand 1
GMB-475, also known as PROTAC BCR-ABL1 ligand 1, allosterically targets and binds to the BCR-ABL1 protein. It effectively recruits the E3 ligase Von Hippel-Lindau, leading to the ubiquitination and subsequent degradation...
TargetMol